Want to dive into Scott Alexander's work and his thousands of blog posts? This fan website lets you sort and do semantic search through the whole codex. Enjoy!

See also Top Posts and All Tags.

Or pick a range
–
min
Blog
Only
Year
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
Tags
Browse all 5386
Include tag...
Exclude tag...
Links to
Filter by linked site (twitter, substack…)
Remember which posts I've read on this device
2 posts
Date
Length
Likes
Comments
study critique (268) pharmaceutical industry (25) antidepressants (25) drug development (18) clinical trials (16) pharmacology (13) psychiatric medication (7) serotonin (6)

The Vision Of Vilazodone And Vortioxetine

Scott Alexander examines the development and effectiveness of vilazodone and vortioxetine, two antidepressants designed to work faster and better than SSRIs, but which ultimately failed to live up to expectations.

ssc
Jun 15, 2020 3,750 words 0 likes 94 comments Listen · 27 min Read Read
study critique (268) psychiatry (73) genetics (58) depression (45) bad science (30) replication crisis (27) antidepressants (25) pharmacogenomics (2)

5-HTTLPR: A Pointed Review

Scott examines how the 5-HTTLPR gene was wrongly linked to depression for years, discussing the implications for psychiatric research and genetic testing products.

ssc
May 7, 2019 3,284 words 0 likes 155 comments Listen · 24 min Read Read
Per page:
Showing 1 to 2 of 2 results
Get these search results in an EPUB

Your filters match 2 posts.

Posts to include
–
Leave empty to keep the defaults. Range cannot exceed 500 posts.
Download now

Generates an EPUB right now and downloads it to your device.

Send to email

Generates an EPUB in the background and emails you a temporary download link.

Your email is not shared with anyone.

Email address

To send to your Kindle, just use this link.