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neurotransmitters (3)
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study critique (272)
book review (224)
AI (113)
economics (105)
effective altruism (105)
education (93)
creative writing (92)
debate (92)
forecasting (91)
politics (89)
prediction markets (89)
science (85)
AI safety (82)
media criticism (76)
neuroscience (76)
rationality (76)
psychiatry (73)
psychology (72)
mental health (69)
highlights from the comments (68)
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domain: slatestarcodex.com (1129 posts)
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3 posts
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AI alignment (42) relationships (12) happiness (11) neurotransmitters (3) drug tolerance (3) prediction error (2)

Unpredictable Reward, Predictable Happiness

Scott examines two types of happiness - one affected by predictability and one that persists - through various examples and neuroscientific concepts.

acx
Sep 13, 2022 3,488 words 156 likes 234 comments Listen · 26 min Read Read Opened Opened
schizophrenia (31) drug development (18) psychiatric research (8) antipsychotics (6) NMDA receptors (5) drug side effects (5) neurotransmitters (3) clozapine (2)

Why Is Clozapine So Great?

Scott explores the theory that clozapine's unique effectiveness in treating schizophrenia may be due to its combined action on dopamine and glutamate systems, potentially opening avenues for safer treatments.

ssc
Jul 27, 2017 1,148 words 0 likes 27 comments Read Read Opened Opened
psychiatry (73) depression (45) antidepressants (25) serotonin (6) medical communication (5) neurotransmitters (3) scientific criticism (3) brain chemistry (2)

Chemical Imbalance

Scott Alexander defends psychiatry's use of 'chemical imbalance' theory, arguing it was meant to emphasize depression's biological basis rather than claiming a simple serotonin deficiency.

ssc
Apr 5, 2015 4,675 words 0 likes 248 comments Read Read Opened Opened
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