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study critique (270)
book review (221)
AI (112)
economics (105)
effective altruism (105)
education (93)
creative writing (91)
debate (89)
forecasting (89)
politics (89)
prediction markets (88)
science (85)
AI safety (79)
media criticism (76)
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rationality (76)
psychiatry (73)
psychology (72)
mental health (69)
highlights from the comments (68)
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2 posts
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psychopharmacology (7) drug addiction (5) drug mechanisms (3) phenibut (2) anxiety treatment (2)

Know Your Gabapentinoids

Scott Alexander compares three gabapentinoid drugs (gabapentin, pregabalin, and phenibut), exploring their effects, mechanisms, and the mysteries surrounding their differing efficacies despite chemical similarities.

ssc
Jul 18, 2019 2,297 words 0 likes 101 comments Listen · 17 min Read Read
placebo effect (24) addiction (21) nootropics (13) self-experimentation (9) survey results (8) LSD (8) modafinil (5) drug effectiveness (4) Adderall (3) phenibut (2)

2016 Nootropics Survey Results

Scott Alexander presents results from a survey of 850 people rating various nootropics, showing a range of perceived effectiveness and exploring addiction potential for some substances.

ssc
Mar 1, 2016 1,606 words 0 likes 212 comments Read Read
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