A review of 'The Family That Couldn't Sleep' by D. T. Max, discussing its exploration of prion diseases and their impact, with updated perspectives on the book's conclusions. Longer summary

This review discusses 'The Family That Couldn't Sleep' by D. T. Max, a book about prion diseases published in 2006. The review covers the book's exploration of various prion diseases, including fatal familial insomnia, kuru, mad cow disease, and chronic wasting disease. It highlights the book's focus on the historical, scientific, and cultural aspects of these diseases, as well as the key figures involved in prion research. The reviewer also provides updated information and critiques some of the book's conclusions in light of more recent research. Shorter summary

Scott Alexander attempts to replicate a poll claiming high rates of COVID vaccine deaths, finds much lower rates, and concludes such polls are unreliable due to bias. Longer summary

Scott Alexander attempts to replicate a poll claiming high rates of COVID vaccine-related deaths. He conducts his own survey and finds much lower rates, investigates possible reasons for the discrepancy, and concludes that such polls are unreliable due to political bias and statistical misunderstanding. Scott's survey shows 0.6% of respondents reporting a vaccine-related death in their family, compared to 8.5% in the original poll. He follows up with respondents who reported deaths, finding most cases involve elderly individuals, and the numbers are consistent with normal death rates. Shorter summary

Scott Alexander examines the current research on Long COVID, analyzing its prevalence, symptoms, and potential impacts to assess personal risk and societal implications. Longer summary

Scott Alexander reviews the current research on Long COVID, examining its prevalence, symptoms, duration, and impact on different groups. He explores various studies, discusses potential mechanisms, and evaluates the psychosomatic argument. The post concludes with an assessment of personal risk and comparisons to other post-viral syndromes, emphasizing the uncertainties still surrounding Long COVID. Shorter summary

Scott Alexander directs readers to his essay on Works in Progress examining why suicide rates didn't increase during the COVID-19 pandemic as expected. Longer summary

Scott Alexander refers readers to his essay published on Works in Progress, which discusses the unexpected trend of suicides during the COVID-19 pandemic. The essay, titled 'Why didn't suicides rise during Covid?', likely explores the counterintuitive finding that suicide rates did not increase as many had predicted during the global health crisis. While the post itself doesn't provide details, it suggests an in-depth analysis of suicide statistics, mental health trends, and potential explanations for this phenomenon during the pandemic. Shorter summary

Scott Alexander writes a humorous poem about getting the COVID-19 vaccine, set to a Les Misérables tune, exploring lockdown frustrations and the complexities of returning to normalcy. Longer summary

This post is a creative writing piece in the form of verses set to the tune of a song from Les Misérables. It humorously depicts the experience of getting the COVID-19 vaccine and the conflicting desires between citizens wanting freedom and epidemiologists urging continued caution. The verses highlight various frustrations with lockdowns, and end with the narrator receiving the vaccine but still being advised to follow restrictions. The piece concludes with the narrator expressing a sense of freedom and resentment towards the FDA for delays in vaccine approval. Shorter summary

Scott Alexander analyzes the COVID-19 pandemic's progress, predicts future waves, and speculates on its long-term impact and transition to an endemic disease. Longer summary

Scott Alexander discusses the current state and future predictions for the COVID-19 pandemic in the US. He outlines the past waves of infections, predicts future waves due to new virus strains, analyzes vaccine efficacy against these strains, and speculates on how the pandemic might eventually transition to an endemic seasonal illness like the flu. He also touches on potential long-term societal changes and makes several specific predictions about future developments. Shorter summary

Scott Alexander discusses the trade-offs between accuracy and liability in medical information, extending the analysis to public health experts and the role of expertise in society. Longer summary

Scott Alexander explores the challenges of providing accurate medical information online, using his own experience with a psychiatry database and comparing it to WebMD. He argues that larger, more legitimate sources like WebMD and government agencies often provide less useful information due to liability concerns and political pressures. The post then extends this analysis to public health experts like Dr. Fauci, suggesting that while they may not always provide the best advice, they serve an important role as 'legibly mediocre' sources of information in a complex system. Scott concludes that while the current system of expertise is flawed, it's better than alternatives and deserves some appreciation. Shorter summary

Scott Alexander discusses various aspects of the COVID-19 pandemic, including strategies, mysteries, controversies, and global impacts. Longer summary

This blog post discusses various aspects of the COVID-19 pandemic, including the 'hammer and dance' strategy, smoking cessation, mysteries surrounding Japan's low case numbers, takeout food safety, ventilator numbers, the UK's policy reversal, density and infection rates, hydroxychloroquine controversy, concerns about developing countries, donation opportunities, cost-benefit analysis of lockdowns, US stimulus bill negotiations, and media coverage of the pandemic across the political spectrum. The post also includes short links to other coronavirus-related news and developments. Shorter summary

Scott Alexander provides updates and speculations on various aspects of the COVID-19 pandemic, including case estimates, strategies, medical issues, and societal responses. Longer summary

This blog post provides updates and speculations on various aspects of the COVID-19 pandemic. It covers topics such as estimating the true number of cases, the lack of a clear endgame strategy, the effectiveness of 'flattening the curve', differentiating COVID-19 from flu symptoms, the use of anti-inflammatory drugs, ventilator shortages, disease seasonality, the need for better data, and the Bay Area's response to the crisis. The post also includes short links to other coronavirus-related news and observations. Shorter summary

Scott Alexander examines conflicting narratives about cancer treatment progress, analyzing data to show that while some improvements are due to social factors, there's evidence of genuine advancements in cancer treatment and outcomes. Longer summary

This post examines the progress made in the 'War on Cancer' by analyzing cancer incidence rates, mortality rates, and five-year survival rates. Scott Alexander explores two competing narratives: one suggesting significant progress and another claiming limited success. He delves into the data, considering factors like age adjustment, smoking trends, and early detection biases. The analysis reveals that while some improvements are due to social factors like reduced smoking, there's evidence of genuine progress in cancer treatment. Stage-specific survival rates have improved, and studies adjusting for various confounders still show advancements. The post concludes that while progress may not meet the grand expectations set in the past, there has been a gradual but real improvement in cancer treatment and outcomes. Shorter summary

The post highlights the effectiveness of bednets in combating malaria in Africa, citing impressive statistics and encouraging donations to continue this progress. Longer summary

The post discusses the significant impact of malaria control efforts, particularly the use of insecticide-treated bednets, in Africa between 2000 and 2015. It cites a Nature study and comments from Giving What We Can, highlighting that bednets have prevented around 450 million cases of malaria and contributed to saving 6.2 million lives. The author expresses enthusiasm about humanity's progress against malaria and shares that they donated a thousand bednets, encouraging others to donate to the Against Malaria Foundation. Shorter summary

A satirical future op-ed argues that not giving children 'super-enhancement gene therapy' is child abuse, mirroring current pro-vaccination arguments. Longer summary

This satirical post, written as if from the future year 2065, critiques current anti-vaccination arguments by applying them to a hypothetical future technology: super-enhancement designer baby gene therapy. The author, posing as a bioethicist, argues that not giving children this therapy is child abuse and a public health issue. The post mimics common pro-vaccination arguments, citing increased crime rates, car accidents, and disease outbreaks as consequences of not enhancing children. It concludes by calling for severe restrictions on unenhanced children and punishment for parents who refuse the therapy. The satire aims to highlight the absurdity of current anti-vaccination arguments by applying similar logic to a more extreme scenario. Shorter summary

Scott Alexander argues that biological solutions to societal problems may be more effective and easier to implement than social interventions, challenging common perceptions about mutability of human characteristics. Longer summary

Scott Alexander challenges the stereotype that the Left believes human characteristics are socially determined and mutable, while the Right believes they are biologically determined and fixed. He argues that society is actually very difficult to change, while biological factors can often be more easily addressed. He provides examples such as drug abuse, obesity, and poor school performance, where social interventions have largely failed but biological solutions (like banning lead or vitamin supplementation) have shown promising results. The post suggests that we should not dismiss biological explanations and solutions to societal problems, as they may be more tractable than purely social approaches. Shorter summary

Scott Alexander presents a diverse collection of recent news items, studies, and interesting facts, covering topics from public health to economics to quirky trivia. Longer summary

This post is a collection of diverse news items, studies, and interesting facts curated by Scott Alexander. It covers a wide range of topics including public health policies, economics, scientific discoveries, social issues, and quirky facts. Scott provides brief commentary on many of the items, often with a touch of humor or irony. The post doesn't have a central theme but rather serves as a roundup of interesting information Scott has come across recently. Shorter summary

Scott Alexander argues that e-cigarettes are likely replacing regular cigarettes rather than non-smoking, making them beneficial for public health despite government attempts to ban them. Longer summary

Scott Alexander discusses the concept of 'funging' and how it applies to e-cigarettes. He argues that e-cigarettes are likely replacing regular cigarettes rather than non-smoking, making them a net positive for public health. The post criticizes governments trying to ban e-cigarettes, arguing that while they may be addictive, they are far less harmful than regular cigarettes. Scott also touches on the cognitive enhancement effects of nicotine and his personal stance on addiction and substance use. The tone is analytical and somewhat sardonic, especially when discussing government policies. Shorter summary