Want to dive into Scott Alexander's work and his thousands of blog posts? This fan website lets you sort and do semantic search through the whole codex. Enjoy!
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Josh Morrison argues that AI superforecasting could transform FDA drug approval by replacing subjective expert judgment with objective, quantitative predictions about drug safety and efficacy.
Scott Alexander examines Zulresso and Zuranolone, two neurosteroid drugs for postpartum depression, discussing their efficacy, challenges, and potential future applications.
Scott Alexander critiques the FDA approval of esketamine for depression, discussing issues with drug development, efficacy, cost, and administration requirements.