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study critique (268) book review (219) bad science (30) research methodology (26) book review contest (25) drug development (18) scientific publishing (4) Alzheimer's disease (3) peer review (3)

Your Review: Of Mice, Mechanisms, and Dementia

A detailed review of a 1995 paper introducing the PDAPP mouse model for Alzheimer's disease, examining how its limitations were overlooked and shaped decades of potentially misguided Alzheimer's research.

acx
Jul 11, 2025 7,754 words 184 likes 170 comments Listen · 48 min Read Read
survey analysis (41) schizophrenia (30) autism (28) optical illusions (11) transgender (10) NMDA receptors (5) estrogen (2)

Why Are Transgender People Immune To Optical Illusions?

Scott Alexander hypothesizes a link between transgender identity, optical illusions, and NMDA receptor function, based on survey data and existing research on schizophrenia and autism.

ssc
Jun 28, 2017 3,120 words 0 likes 356 comments Read Read
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