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antipsychotics (6)
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study critique (270)
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6 posts
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Contra Skolnick On Schizophrenia Microbes

Scott Alexander refutes Stephen Skolnick's theory that schizophrenia is caused by gut microbes rather than genetics, showing why the evidence better supports schizophrenia being a complex genetic neurodevelopmental disorder.

acx
Jun 30, 2025 1,619 words 256 likes 180 comments Listen · 11 min Read Read

Treating The Prodrome

The post examines the theory of treating schizophrenia's prodrome stage, exploring how early intervention might prevent full-blown schizophrenia and discussing the biological mechanisms behind the disease's progression.

ssc
Sep 20, 2018 2,918 words 0 likes 103 comments Listen · 21 min Read Read

Why Is Clozapine So Great?

Scott explores the theory that clozapine's unique effectiveness in treating schizophrenia may be due to its combined action on dopamine and glutamate systems, potentially opening avenues for safer treatments.

ssc
Jul 27, 2017 1,148 words 0 likes 27 comments Read Read

Tolerance Troubles

Scott Alexander explores the complexities and inconsistencies of drug tolerance in psychiatry, highlighting how different drugs can produce varying tolerance effects across individuals.

ssc
Aug 15, 2016 2,119 words 0 likes 344 comments Read Read

Highlights From My Notes From Another Psychiatry Conference

Scott Alexander shares insights and critiques from a psychiatry conference, covering topics from medication prescribing rights to new monitoring technologies and research methodologies.

ssc
Mar 27, 2015 1,782 words 0 likes 171 comments Read Read

Weird Psychiatric Ads Of The Seventies

Scott Alexander presents and humorously critiques a series of strange psychiatric drug advertisements from the 1960s and 1970s, highlighting their peculiar imagery and messaging.

ssc
Jul 28, 2014 1,628 words 0 likes 36 comments Read Read
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