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drug tolerance (3)
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study critique (270)
book review (221)
AI (112)
economics (105)
effective altruism (105)
education (93)
creative writing (91)
debate (89)
forecasting (89)
politics (89)
prediction markets (88)
science (85)
AI safety (79)
media criticism (76)
neuroscience (76)
rationality (76)
psychiatry (73)
psychology (72)
mental health (69)
highlights from the comments (68)
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3 posts
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AI alignment (39) relationships (12) happiness (11) neurotransmitters (3) drug tolerance (3) prediction error (2)

Unpredictable Reward, Predictable Happiness

Scott examines two types of happiness - one affected by predictability and one that persists - through various examples and neuroscientific concepts.

acx
Sep 13, 2022 3,488 words 156 likes 234 comments Listen · 26 min Read Read
survey analysis (42) nootropics (13) supplement efficacy (6) modafinil (5) drug tolerance (3) Zembrin (2) caffeine alternatives (2)

Nootropics Survey 2020 Results

Scott Alexander presents results from his 2020 nootropics survey, covering effectiveness ratings, tolerance, and user experiences with various substances.

acx
Apr 28, 2021 1,949 words 97 likes 147 comments Listen · 16 min Read Read
psychiatry (73) antidepressants (25) addiction (21) pharmacology (13) antipsychotics (6) drug tolerance (3) benzodiazepines (2)

Tolerance Troubles

Scott Alexander explores the complexities and inconsistencies of drug tolerance in psychiatry, highlighting how different drugs can produce varying tolerance effects across individuals.

ssc
Aug 15, 2016 2,119 words 0 likes 344 comments Read Read
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