Scott Alexander proposes a theory of depression as a recalibrated happiness set point, drawing parallels with fever and anorexia, to explain why depressed people seek out sad stimuli.

Scott reviews a book on culture-bound syndromes, expanding the discussion to how all mental illnesses are influenced by culture to varying degrees.

Scott Alexander reviews 'Crazy Like Us', exploring how Western mental health concepts spread globally and whether raising awareness of mental health problems might make them worse.

Scott Alexander explores anorexia's biological aspects beyond cultural factors, presenting and analyzing del Giudice's 'self-starvation cycle' theory as a more comprehensive explanation of the disorder.

Scott Alexander speculates that anorexia might be caused by a distorted metabolic set point, similar to but opposite of obesity's mechanisms.