Scott Alexander refutes Stephen Skolnick's theory that schizophrenia is caused by gut microbes rather than genetics, showing why the evidence better supports schizophrenia being a complex genetic neurodevelopmental disorder.

Scott Alexander critically examines pharmacogenomic testing for antidepressants, particularly the GeneSight test, expressing skepticism about its current effectiveness and validity.

A links roundup examining various scientific studies, social developments, and historical findings, with a particular focus on recent research about confounding variables and replication issues in science.

Scott examines how rare but severe drug side effects often lead to underprescription compared to drugs with common but less severe side effects, potentially resulting in suboptimal patient care.

Scott Alexander critically examines the Institute of HeartMath, exposing a mix of misused science and pseudoscience in their 'heart coherence' claims and practices.

Scott Alexander critiques mass-produced medical recommendations, showing how they can oversimplify or misrepresent scientific evidence using vitamin D and niacin as examples.