A guest post defending the amyloid hypothesis of Alzheimer's disease, explaining why amyloid is likely the root cause despite recent criticism and discussing why early treatments have only been partially effective.

A review of 'Two Arms and a Head', a paraplegic's memoir and argument for physician-assisted suicide, exploring the book's content and the broader debate around Medical Assistance in Dying.

Scott Alexander responds to critiques of his 2021 ivermectin analysis, acknowledging some errors but maintaining his conclusion that ivermectin likely doesn't work for COVID-19.

Scott summarizes and responds to comments on his previous article about FDA approval of Paxlovid, acknowledging some valid points while maintaining his criticism of the approval process.

Scott Alexander analyzes ivermectin studies for COVID-19, finding most positive results likely due to methodological flaws, fraud, or confounding by parasitic infections.