Scott Alexander hypothesizes a link between transgender identity, optical illusions, and NMDA receptor function, based on survey data and existing research on schizophrenia and autism. Longer summary

Scott Alexander explores a potential link between transgender identity, optical illusions, and NMDA receptor function in the brain. He presents survey data suggesting that transgender individuals, like those with schizophrenia and autism, are less susceptible to certain optical illusions. He hypothesizes that this might be related to NMDA receptor hypofunction, which is also associated with dissociation, a common experience among transgender people. The post explores how estrogen, which enhances NMDA function, alleviates dissociation in trans women. Scott connects these findings to broader research on NMDA receptors in schizophrenia and autism, noting the higher prevalence of these conditions in transgender populations. The post concludes with several caveats and suggestions for future research to validate these speculative connections. Shorter summary

Scott Alexander explores the hidden prevalence of misery in society, using his psychiatric experience and statistical analysis to argue that suffering is more widespread than commonly perceived. Longer summary

Scott Alexander reflects on the prevalence of misery and hardship in society, based on his experiences as a psychiatrist. He describes typical patient profiles that showcase severe life difficulties, and contrasts this with the tendency of people to socially filter for those similar to themselves. The post then presents statistics on various forms of suffering and runs a simulation to estimate how common these issues are in the general population. The author concludes that the world is likely much worse than most people realize, even in seemingly prosperous areas, and cautions against dismissing the problems of any particular group. He suggests that this realization might motivate people to contribute to efforts to improve the world, such as through charitable donations. Shorter summary

Scott Alexander critiques media reporting of scientific studies, showing how the same study can lead to vastly different headlines and interpretations, often misrepresenting the actual findings. Longer summary

Scott Alexander critiques media reporting of scientific studies, focusing on two examples: a study about parental time spent with children and another about weight discrimination. He shows how different media outlets can present the same study with vastly different, even contradictory headlines. In the weight discrimination study, he points out how the actual findings were much less significant than the media portrayed, with many important measures showing no discrimination. Scott argues that the process from conducting a study to its media reporting allows for too many 'degrees of freedom', resulting in headlines that may not accurately reflect the study's actual findings. He concludes by emphasizing the importance of reading beyond headlines and abstracts to understand scientific studies accurately. Shorter summary

Scott shares a diverse collection of interesting links spanning science, history, and current events, with commentary on research methodologies and unexpected findings. Longer summary

A collection of interesting links and studies across various topics. The post covers scientific studies (like ego depletion and male variability), historical curiosities (like Russian Somalia and Project Oilsand), current events (Jeremy Corbyn's election), and various social and political developments. Scott presents each item with brief commentary, often highlighting interesting methodologies or unexpected findings. The post maintains a mix of serious academic content and more lighthearted observations, frequently noting clever research designs or counterintuitive findings. Shorter summary