The post explores the complex relationship between smoking and schizophrenia, critiquing conflicting studies and cautioning against hasty conclusions about nicotine's effects on schizophrenia risk. Longer summary

This post examines the relationship between smoking and schizophrenia. It starts by noting the high prevalence of smoking among schizophrenics and discusses various theories for this, including the self-medication hypothesis. The author then analyzes two conflicting studies on whether smoking causes or prevents schizophrenia. One study suggests smoking increases risk, while another, which controls for confounders, indicates smoking may decrease risk. The post criticizes how the first study, despite being newer, ignores the contradictory findings of the second study. The author expresses frustration with this scientific approach and cautions against pushing people at risk of schizophrenia away from nicotine without stronger evidence. The post ends by noting that smoking definitely decreases Parkinson's Disease risk and reiterating that tobacco smoking is still harmful overall. Shorter summary

Scott Alexander explores the hidden prevalence of misery in society, using his psychiatric experience and statistical analysis to argue that suffering is more widespread than commonly perceived. Longer summary

Scott Alexander reflects on the prevalence of misery and hardship in society, based on his experiences as a psychiatrist. He describes typical patient profiles that showcase severe life difficulties, and contrasts this with the tendency of people to socially filter for those similar to themselves. The post then presents statistics on various forms of suffering and runs a simulation to estimate how common these issues are in the general population. The author concludes that the world is likely much worse than most people realize, even in seemingly prosperous areas, and cautions against dismissing the problems of any particular group. He suggests that this realization might motivate people to contribute to efforts to improve the world, such as through charitable donations. Shorter summary