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Tag: GLP-1 drugs

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3 posts found
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Jul 22, 2026
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25 min 3,748 words 441 comments 219 likes podcast (22 min)
Scott shares his monthly collection of interesting links from around the internet, covering topics from Jeremy Bentham's linguistic legacy to AI developments, with characteristic commentary and fact-checking caveats. Longer summary
This is Scott's monthly 'Links' post, a curated collection of interesting articles, studies, and social media posts from around the internet. The links span a wide range of topics including historical curiosities (Jeremy Bentham's word inventions, beard-wearing persecution in 19th century America), scientific oddities (a mushroom that causes gnome hallucinations), AI developments (mathematical proofs, constrained writing, dating apps), current events (Berkeley's housing permits, GLP-1 weight retention), and cultural phenomena (the Monet/AI art prank). Scott includes his typical epistemic disclaimers about not having verified all links independently and provides commentary throughout. The post ends with a note that he accumulated too many links and will publish the second half next week. Shorter summary
Mar 12, 2025
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11 min 1,644 words 487 comments 730 likes podcast (11 min)
Scott analyzes the implications of the FDA ending compounded GLP-1 weight loss drugs, which have provided a cheaper alternative to official channels for the past three years, and examines various responses from both compounding pharmacies and pharmaceutical companies. Longer summary
Scott discusses the upcoming end to compounded GLP-1 weight loss drugs in the US, as the FDA declares the shortage over. He explains how for the past three years, compounding pharmacies have provided these drugs at $200/month compared to the official $1000/month price, helping about 2 million Americans. The post explores various strategies companies are using to try to continue providing cheaper alternatives, and how pharmaceutical companies are responding with their own direct-to-consumer models. Scott concludes by noting how this experiment in semi-free-market medicine has shown that a less regulated supply chain can work effectively. Shorter summary
Aug 13, 2024
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29 min 4,403 words 567 comments 1,016 likes podcast (27 min)
Scott Alexander examines the surprisingly broad effects of GLP-1 drugs like Ozempic, exploring their mechanisms and speculating on why they seem to impact so many different conditions. Longer summary
Scott Alexander explores the wide-ranging effects of GLP-1 receptor agonist medications like Ozempic, which are approved for diabetes and obesity but show promise for many other conditions. He delves into the mechanisms behind their effects on diabetes, weight loss, and addiction, speculating on why these drugs seem to have such broad impacts. The post discusses how GLP-1 drugs work in the brain to reduce hunger and dampen reward systems, potentially explaining their effects on addiction. Scott also touches on their anti-inflammatory properties and potential benefits for neurodegenerative diseases, while cautioning that some reported effects may not replicate. Shorter summary
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