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3 posts found
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Apr 16, 2024
acx
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12 min 1,707 words 160 comments 156 likes podcast (11 min)
Scott Alexander updates on Lumina probiotic, discussing FDA trials, effectiveness, potential risks, and his nuanced stance on the product. Longer summary
Scott Alexander provides updates on Lumina, a genetically modified anti-tooth-decay bacterium. He clarifies information about FDA testing, discusses rat trial results, reports on recent colonization studies, addresses potential side effects, and shares some anecdotal results. Scott also explains his stance on Lumina, emphasizing that while he sees potential benefits, he doesn't fully endorse it and acknowledges the uncertainties and risks involved. Shorter summary
Mar 28, 2024
acx
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118 min 18,207 words 905 comments 369 likes podcast (95 min)
Scott Alexander reviews a $100,000 debate on COVID-19 origins, where the zoonotic hypothesis unexpectedly won against the lab leak theory. Longer summary
Scott Alexander reviews a debate on the origins of COVID-19 between Saar Wilf, who supports the lab leak hypothesis, and Peter Miller, who argues for zoonotic origin. The debate was part of a $100,000 challenge by Wilf's Rootclaim project. Miller won decisively, with both judges ruling in favor of zoonotic origin. Alexander analyzes the debate format, arguments, and aftermath, discussing issues with Bayesian reasoning, extreme probabilities, and the challenges of resolving complex scientific questions through debate. Shorter summary
Feb 17, 2023
acx
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31 min 4,739 words 225 comments 156 likes podcast (27 min)
Scott Alexander reviews the evidence for declining sperm counts, discussing major studies, criticisms, and potential causes, while remaining uncertain about the true extent and reasons for any decline. Longer summary
Scott Alexander examines the evidence for declining sperm counts worldwide, discussing the major studies, potential causes, and criticisms of the hypothesis. He explores the methodology of sperm count studies, regional variations, possible explanations like plastics and pesticides, and animal data. While acknowledging the noisy data and potential confounders, he concludes that there's suggestive evidence for a decline but remains uncertain about its magnitude and causes. Shorter summary
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