Scott Alexander responds to comments and criticism on his earlier post about 'Missing Heritability', discussing issues like gene-environment interactions, sequencing technology limitations, and the use of polygenic scores across ancestry groups.

Scott Alexander critically examines pharmacogenomic testing for antidepressants, particularly the GeneSight test, expressing skepticism about its current effectiveness and validity.

A collection of interesting links covering science, education, politics and culture, with Scott Alexander's commentary and analysis on each.

Scott Alexander explains how to interpret 23andMe genetic data using SNPedia, listing various SNPs and their alleged effects while emphasizing the unreliability of such interpretations.

Scott Alexander examines overpriced medical products like Lovaza and Deplin, arguing they serve a purpose in the medical system, but criticizes exorbitant BRCA gene testing prices as harmful.

Scott Alexander critiques a study suggesting knowledge of ApoE4 gene status affects memory performance, arguing the results may be due to priming or stereotype threat rather than actual memory decline.

Scott Alexander drafts a letter to the FDA arguing against their decision to halt 23andMe's genetic testing services, highlighting the benefits and addressing the FDA's concerns.