Scott Alexander provides a comprehensive guide on ketamine as a depression treatment, covering administration methods, effectiveness, safety, dosage, and potential side effects.

Scott Alexander maintains a list of significant mistakes in his blog posts, providing corrections and updates in reverse chronological order.

The post explores how emotional learning creates hard-to-update mental models, drawing parallels between psychotherapy, psychedelics, and rationality techniques in overcoming these 'mental mountains'.

Scott reviews a paper proposing that psychedelics work by relaxing priors in the brain, potentially treating mental illness but also risking side effects.

Scott explores the theory that clozapine's unique effectiveness in treating schizophrenia may be due to its combined action on dopamine and glutamate systems, potentially opening avenues for safer treatments.