Scott analyzes the implications of the FDA ending compounded GLP-1 weight loss drugs, which have provided a cheaper alternative to official channels for the past three years, and examines various responses from both compounding pharmacies and pharmaceutical companies. Longer summary

Scott discusses the upcoming end to compounded GLP-1 weight loss drugs in the US, as the FDA declares the shortage over. He explains how for the past three years, compounding pharmacies have provided these drugs at $200/month compared to the official $1000/month price, helping about 2 million Americans. The post explores various strategies companies are using to try to continue providing cheaper alternatives, and how pharmaceutical companies are responding with their own direct-to-consumer models. Scott concludes by noting how this experiment in semi-free-market medicine has shown that a less regulated supply chain can work effectively. Shorter summary

Scott shares various interesting links and news items from January 2025, covering topics from AI development and politics to historical curiosities and economic trends. Longer summary

This links post covers a wide array of topics from January 2025, with Scott providing commentary and analysis on each. The links include discussions about running for Congress, AI development and safety, dating advice, psychiatric diagnoses, and various economic and technological developments. Scott often adds his own insights and sometimes skepticism to the claims being discussed. The post also includes several historical curiosities and social observations, maintaining a mix of serious analysis and lighter interesting facts. Shorter summary

Scott shares 55 interesting links covering topics from AI poetry to religious movements, including updates on various projects, unusual historical events, and current developments in technology, politics, and society. Longer summary

This is Scott's monthly links post for December 2024, collecting various interesting stories and developments. The links cover a wide range of topics, from Steven Seagal's bizarre life trajectory to developments in AI and technology, including updates on previous ACX topics and grants. Many links relate to ongoing discussions in the rationalist and EA communities, including debates about effective altruism and charitable giving. The post also includes various curiosities from history, culture, and current events, with Scott often providing his own analysis or perspective on the items shared. Shorter summary

A compilation of 50 diverse news items and links from September 2024, covering topics from politics and economics to science and technology. Longer summary

This post is a compilation of 50 diverse links and news items from September 2024. It covers a wide range of topics including politics, science, technology, economics, and social issues. Some notable items include discussions on kidney donation compensation, personality genetics, fertility rates in Israel, drug decriminalization in Oregon, AI regulation in California, and various political and economic analyses. The post also includes commentary on recent studies, books, and social phenomena. Shorter summary

Scott Alexander examines the surprisingly broad effects of GLP-1 drugs like Ozempic, exploring their mechanisms and speculating on why they seem to impact so many different conditions. Longer summary

Scott Alexander explores the wide-ranging effects of GLP-1 receptor agonist medications like Ozempic, which are approved for diabetes and obesity but show promise for many other conditions. He delves into the mechanisms behind their effects on diabetes, weight loss, and addiction, speculating on why these drugs seem to have such broad impacts. The post discusses how GLP-1 drugs work in the brain to reduce hunger and dampen reward systems, potentially explaining their effects on addiction. Scott also touches on their anti-inflammatory properties and potential benefits for neurodegenerative diseases, while cautioning that some reported effects may not replicate. Shorter summary

A wide-ranging collection of 40 news items and interesting facts, covering AI, politics, science, economics, and culture, with the author's commentary. Longer summary

This post is a collection of 40 diverse links and news items covering topics such as AI developments, politics, science, technology, economics, and culture. It includes updates on OpenAI and Google's AI projects, discussions on religious phenomena, analyses of social and economic trends, and various interesting facts and anecdotes. The author provides commentary and context for many of the items, often with a mix of humor and critical analysis. Shorter summary