Scott Alexander investigates the unexpectedly high prevalence of joint hypermobility in transgender individuals, exploring various theories and presenting survey data on the phenomenon. Longer summary

Scott Alexander explores the puzzling connection between transgender identity and hypermobile joints, particularly Ehlers-Danlos syndrome (EDS). He presents four theories to explain this correlation: 1) It's a spurious result due to 'Instagrammable' conditions clustering together, 2) Estrogen effects on joints in trans women, 3) Genetic link between gender divergence and joint issues, and 4) Autism as a shared causative factor. Scott favors a theory linking proprioception issues to different reasoning styles, potentially leading to both autism and transgender identity. He presents data from his own survey showing higher rates of joint issues in trans respondents, though with some limitations. The post concludes with plans for further investigation in future surveys. Shorter summary

A diverse collection of links covering recent studies, unusual historical events, technological developments, and various curiosities across multiple fields. Longer summary

This post is a collection of various links and news items on diverse topics. It covers studies on pornography's effects, unusual military proposals, charter schools' success, climate change predictions, animal rights, restorative justice in schools, parenting advice, sexual selection theory, AI-generated content, breastfeeding patterns, visualization of classical music, Soviet whaling, cancel culture, housing legislation, embryo screening, retractions of scientific studies, gene drives, drug pricing, UFO sightings, cryopreservation, air conditioning efficiency, genetic testing for medication response, social justice terminology trends, napping benefits, nootropics survey results, Bitcoin price surge, transformer architecture in machine learning, fact-checking errors in popular books, challenges to persistence research, fringe ideologies in Japan, AI progress on language understanding, climate change risks, and various other curiosities and scientific findings. Shorter summary

Scott Alexander critiques the autism rights movement's opposition to curing autism, arguing that severe cases cause immense suffering that justifies continued research into cures. Longer summary

Scott Alexander discusses the autism rights movement and their opposition to curing autism. While supporting most of their work, he disagrees with the stance against cures. He argues that severe autism causes immense suffering that cannot be alleviated solely through better treatment, and that research into cures should continue. He acknowledges the benefits autism can bring, but believes the costs outweigh them for many individuals. The post examines outcomes for autistic adults, issues with institutionalization, and ethical considerations around curing or preventing autism. Shorter summary

A collection of interesting links from October 2014 with Scott's commentary, covering topics from Russian deforestation to North Korean politics to scientific research. Longer summary

This is a links post where Scott Alexander shares various interesting articles and news items from October 2014. He covers topics ranging from environmental issues in Russia, food safety mishaps, basic income problems, North Korean politics, and scientific research. The post includes both serious topics like sexual assault prevention research and lighter ones like football chants and textbook covers. Scott provides commentary and context for each link, sometimes with his characteristic humor. Shorter summary

Scott analyzes various criticisms of antidepressants, concluding they have modest but real benefits over placebo, with important considerations about side effects and efficacy. Longer summary

This post examines various criticisms of SSRIs and antidepressants, addressing claims about their efficacy, side effects, and comparisons to placebo and psychotherapy. Scott analyzes studies on antidepressant effectiveness, discussing issues like publication bias, effect sizes, and the meaning of 'clinical significance'. He explores side effects, particularly sexual dysfunction, weight gain, and emotional blunting. The post concludes that while antidepressants are not miracle drugs, they do have a modest but statistically significant benefit over placebo and can be a reasonable option for many people with depression, especially if they understand and prepare for potential side effects. Shorter summary

Scott Alexander presents a roundup of recent scientific and medical studies, covering topics from hallucinations to obesity genetics to schizophrenia treatment. Longer summary

This post is a collection of various scientific and medical studies and news. It covers a range of topics including hallucinations, diet and longevity, gene-environment interactions in psychiatry, life-extending drugs, fibromyalgia, chemical education, drug company tactics, sleep theories, psychotherapy effectiveness, obesity genetics, and schizophrenia treatment. Scott provides brief summaries and commentary on each item, often with a mix of scientific insight and humor. Shorter summary