Scott announces the results of the 2025 ACX Grants round, awarding $1.5 million to 42 projects out of 654 applications, covering areas from genetic engineering and disease prevention to AI safety and educational reform.

Scott responds to three concerns about embryo selection: embryo personhood rights, loss of trait diversity, and the ethics of preventing disabilities, arguing that none of these objections are fatal to the technology.

Scott analyzes the sudden emergence of commercial trait-based embryo selection services, discussing both the scientific validity and ethical implications of selecting embryos for health outcomes, intelligence, and physical traits.

The post explores the Far Out Initiative's goal to eliminate suffering through biotechnology, inspired by a pain-free woman and David Pearce's philosophy.

Scott Alexander explores how evolutionary processes explain the polygenic structure of schizophrenia and other complex traits, addressing concerns about genetic research and implications for future genetic interventions.

Scott Alexander's monthly links post covers diverse topics from AI developments and genetic research to historical anecdotes and local news, with a mix of serious analysis and humor.

Scott Alexander reviews Lantern Bioworks' Lumina, a genetically modified bacterium designed to prevent tooth decay, discussing its science, safety, and commercialization plans.

A review of 'God Emperor of Dune' by Frank Herbert, analyzing its themes of power, AI risk, and human evolution, while drawing parallels to modern concerns about artificial intelligence.

Scott Alexander discusses the birth of the first polygenically-screened baby and explores the current and potential future applications of this technology in IVF.

Scott Alexander argues that Jewish overachievement is real and deserves continued study, countering Noah Smith's attempt to downplay its significance.

A collection of interesting links covering medical research, sociology, politics, and technology, with brief commentary on each item.

Scott Alexander refutes PZ Myers' race car analogy against genetic engineering for intelligence, showing that high IQ positively correlates with many beneficial traits.

Scott Alexander critiques the autism rights movement's opposition to curing autism, arguing that severe cases cause immense suffering that justifies continued research into cures.

A satirical future op-ed argues that not giving children 'super-enhancement gene therapy' is child abuse, mirroring current pro-vaccination arguments.

Scott responds to authors of a Victorian intelligence paper, remaining skeptical of their findings and addressing critiques of his original post on IQ change speeds.