Scott Alexander conducts an experiment playing a word game 800 times under varying CO2 levels, finding no correlation between indoor carbon dioxide and cognitive performance.

Scott Alexander conducts a personal randomized controlled trial of a sleep supplement, finding no significant effect over placebo, but gains insights into his sleep patterns.

Scott Alexander introduces an 'Anxiety Sampler Kit' for testing various anxiety supplements, aiming to personalize treatment and gather data through self-experimentation.

Scott Alexander reports on a survey about nighttime ventilation interventions, finding modest overall improvements but some individual success stories.

Scott Alexander presents results from a survey of 850 people rating various nootropics, showing a range of perceived effectiveness and exploring addiction potential for some substances.

Scott Alexander discusses the online forum Longecity, where users organize group buys of experimental chemicals, seeing it as a risky but intriguing counterbalance to slow drug approval processes.

Scott Alexander critically examines the concept of self-conditioning, expressing skepticism while considering potential benefits and deciding to experiment with the technique.

Scott attempts to test a productivity hack using calligraphy study, but discovers calligraphy itself is captivating, leaving the experiment inconclusive.