A compilation of 55 diverse links and brief commentaries on various topics, including scientific studies, historical anecdotes, cultural phenomena, and technological developments. Longer summary

This post is a collection of 55 diverse links and brief commentaries on various topics, ranging from scientific studies and historical anecdotes to cultural phenomena and technological developments. The author covers subjects such as economic miracles, AI developments, religious trends, and social issues. Many items include claims or studies that the author finds interesting or surprising, often with a skeptical or analytical perspective. The post also includes updates on previous topics discussed by the author and references to other bloggers or researchers in the rationalist and effective altruism communities. Shorter summary

Scott Alexander recounts his experience donating a kidney, from initial motivation to post-surgery recovery, while discussing the broader context of organ donation. Longer summary

Scott Alexander describes his journey to donate a kidney, including his motivations, the medical process, and the challenges he faced. He discusses the effectiveness of kidney donation compared to other forms of altruism, the stigma around mental health in the donation process, and the need for systemic changes to address the kidney shortage. Scott also reflects on the experience of the surgery and recovery, and encourages others to consider donation. Shorter summary

Scott Alexander critiques Ben Hoffman's arguments about Vitamin D dosing, maintaining that it is primarily a bone-related chemical with limited evidence for other benefits. Longer summary

Scott Alexander responds to Ben Hoffman's critique of his views on Vitamin D dosing. He argues that ancestral populations likely received much less Vitamin D from sunlight than Hoffman suggests, and that the doses used in most studies are appropriate. Scott reviews the literature on Vitamin D dosing, discusses various recommendations and debates within the medical community, and explains why he remains skeptical of claims about Vitamin D's non-skeletal benefits, including for COVID-19 treatment. Shorter summary

Scott Alexander examines obscure pregnancy interventions that may improve child outcomes, rating them by evidence quality and potential impact. Longer summary

Scott Alexander reviews various obscure pregnancy interventions that could potentially improve child outcomes, particularly IQ. He rates them in tiers based on evidence strength and potential impact, with Tier 1 being most strongly supported. Key interventions discussed include embryo selection, choline supplementation, avoiding stress and certain substances, and optimizing birth timing. He emphasizes these are extreme measures not meant to induce guilt, and that standard pregnancy advice is still most important. Shorter summary

Scott Alexander examines melatonin's effects, proper dosage, and uses for sleep disorders and circadian rhythm issues, emphasizing its dual role as a hypnotic and chronobiotic. Longer summary

Scott Alexander provides an in-depth analysis of melatonin, its effects, and proper usage. He explains that melatonin functions as both a hypnotic (inducing sleep) and a chronobiotic (shifting circadian rhythms). The post covers optimal dosing (0.3 mg, much lower than commonly available doses), use in treating circadian rhythm disorders, jet lag, and potential connections to other psychiatric conditions like seasonal affective disorder and depression. Scott also discusses personal experiences with melatonin, including its tendency to cause early waking and vivid dreams in some people. Shorter summary

Scott Alexander offers Christmas shopping recommendations for various products, from balsamic vinegar to nootropics, with personal insights on each item. Longer summary

Scott Alexander provides product recommendations for Christmas shopping, including a link to his Amazon affiliate page. He recommends traditional 18-year balsamic vinegar for its interesting taste, sweatpants that look like regular pants for comfort, xylitol nasal spray for congestion, the Hamilton musical CD, dental floss scythes for easier flossing, Nootropics Depot and Ceretropic online stores for nootropics, and periscope glasses for reading while lying down. He discusses each product's benefits and his personal experiences with them. Shorter summary

Scott Alexander reviews a wide range of treatments for anxiety disorders, from lifestyle changes and therapy to medications and alternative remedies, emphasizing the importance of exploring multiple options. Longer summary

Scott Alexander provides an extensive overview of various treatments for anxiety disorders, covering diet and lifestyle changes, therapy options, conventional medications, and alternative treatments. He emphasizes the importance of lifestyle interventions like exercise and sleep, discusses the efficacy of cognitive-behavioral therapy and exposure therapy, and reviews various medication classes including SSRIs, SNRIs, and benzodiazepines. The post also explores alternative treatments like supplements and experimental drugs, concluding that while no single treatment stands out as extremely effective, there are many options available for those dealing with anxiety. Shorter summary

Scott Alexander offers a comprehensive guide for treating depression, covering professional help, lifestyle changes, and supplements, emphasizing the importance of persistence in finding effective treatments. Longer summary

Scott Alexander provides a comprehensive guide for people with depression, covering diagnosis, treatment options, and self-help strategies. He starts by explaining how to determine if one has depression and strongly recommends seeing a doctor or psychiatrist. He then outlines a step-by-step treatment algorithm for doctors to follow, including various medications and therapies. The post also covers lifestyle interventions, supplements, and other strategies for those who can't or won't see a doctor. Scott emphasizes the importance of persistence in finding effective treatments and reassures readers that depression is often treatable with sufficient effort. Shorter summary