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healthcare costs (22)
study critique (270)
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effective altruism (105)
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study critique (270)
book review (221)
AI (112)
economics (105)
effective altruism (105)
education (93)
creative writing (91)
debate (89)
forecasting (89)
politics (89)
prediction markets (88)
science (85)
AI safety (79)
media criticism (76)
neuroscience (76)
rationality (76)
psychiatry (73)
psychology (72)
mental health (69)
highlights from the comments (68)
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22 posts
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The Ozempocalypse Is Nigh

Scott analyzes the implications of the FDA ending compounded GLP-1 weight loss drugs, which have provided a cheaper alternative to official channels for the past three years, and examines various responses from both compounding pharmacies and pharmaceutical companies.

acx
Mar 12, 2025 1,644 words 730 likes 487 comments Listen · 11 min Read Read

Progesterone Megadoses Might Be A Cheap Zulresso Substitute

Scott Alexander proposes using high-dose oral progesterone as a potential low-cost alternative to Zulresso for treating postpartum depression, based on pharmacological research.

acx
Mar 10, 2022 701 words 53 likes 84 comments Listen · 8 min Read Read

Highlights From The Comments On Health Care Systems

Scott Alexander compiles reader comments on healthcare systems in various countries, discussing economics, drug pricing, and personal experiences.

acx
Jan 27, 2022 9,034 words 57 likes 206 comments Listen · 60 min Read Read

Highlights From The Comments On Aducanumab

Scott Alexander reviews comments on his posts about aducanumab and the FDA, acknowledging some mistakes while defending his overall critique of FDA conservatism.

acx
Aug 20, 2021 6,181 words 57 likes 224 comments Listen · 39 min Read Read

Adumbrations Of Aducanumab

Scott Alexander argues that the FDA is too strict, not too lax, and proposes unbundling FDA approval to allow for more nuanced drug regulation.

acx
Aug 5, 2021 5,328 words 273 likes 622 comments Listen · 34 min Read Read

Peer Review Request: Ketamine

Scott Alexander provides a comprehensive guide on ketamine as a depression treatment, covering administration methods, effectiveness, safety, dosage, and potential side effects.

acx
Jul 19, 2021 7,352 words 42 likes 168 comments Listen · 55 min Read Read

Welcome To The Terrible World Of Prescription-Only Apps

Scott Alexander criticizes the emergence of expensive, prescription-only therapy apps, using Somryst (a CBT-i app) as an example, and warns about the normalization of this trend.

acx
May 12, 2021 2,630 words 128 likes 231 comments Listen · 18 min Read Read

The Amish Health Care System

Scott Alexander examines the Amish health care system, which costs much less than the American system while maintaining good health outcomes, and considers its implications for broader healthcare policy.

ssc
Apr 20, 2020 4,269 words 0 likes 557 comments Listen · 26 min Read Read

Followup On The Baumol Effect: Thanks, O Baumol

Scott Alexander follows up on his critique of a book about the Baumol effect, presenting data that challenges the book's claims about rising wages driving cost increases in education and healthcare.

ssc
Jun 17, 2019 1,940 words 0 likes 186 comments Listen · 15 min Read Read

Book Review: Why Are The Prices So D*mn High?

Scott Alexander reviews a book attributing rising service costs to the Baumol effect, finding it convincing but raising some concerns about conflicting data and affordability issues.

ssc
Jun 10, 2019 1,976 words 0 likes 386 comments Listen · 15 min Read Read

Cost Disease In Medicine: The Practical Perspective

Scott Alexander proposes a hypothetical low-cost psychiatric practice to combat medical cost disease, exploring its potential and the barriers to its implementation.

ssc
Jun 20, 2018 940 words 0 likes 308 comments Listen · 8 min Read Read

Mental Health On A Budget

Scott Alexander offers various strategies for obtaining affordable mental health care and medication in the US, including discount programs, therapy alternatives, and supplement options.

ssc
Apr 25, 2018 2,286 words 0 likes 105 comments Listen · 17 min Read Read

Links 11/17: Sri Linka

A collection of links covering topics from drug regulation and genetic testing to tax reform and AI developments, with Scott's commentary on each item.

ssc
Nov 22, 2017 2,812 words 0 likes 598 comments Read Read

Highlights From The Comments On Cost Disease

Scott Alexander summarizes various responses to his post on 'cost disease', presenting diverse explanations for dramatic cost increases in healthcare, education, and infrastructure.

ssc
Feb 17, 2017 7,862 words 0 likes 406 comments Read Read

Considerations On Cost Disease

Scott Alexander examines the phenomenon of cost disease, where costs for basic services like education and healthcare have increased dramatically without corresponding improvements in quality or wages.

ssc
Feb 9, 2017 7,274 words 0 likes 21 comments Listen · 51 min Read Read

Reverse Voxsplaining: Drugs vs. Chairs

Scott Alexander argues that the EpiPen price hike is due to over-regulation and cronyism in the pharmaceutical industry, not lack of regulation as suggested by Vox.

ssc
Aug 29, 2016 1,657 words 0 likes 737 comments Listen · 12 min Read Read

The Problems With Generic Medications Go Deeper Than One Company

The post examines three major issues with generic medications: barriers to market entry, problematic FDA initiatives, and inconsistent pricing across pharmacies.

ssc
Sep 24, 2015 2,383 words 0 likes 532 comments Read Read

Links 3/15: Duke of URL

A collection of interesting links covering research studies, social issues, economic trends and cultural phenomena that challenged expectations.

ssc
Apr 6, 2015 2,289 words 0 likes 579 comments Read Read

Money, Money, Everywhere, But Not A Cent To Spend

Scott Alexander critiques the inefficiency of psychiatric care for poverty-related issues, suggesting a Basic Income Guarantee as a potentially more effective solution.

ssc
Feb 12, 2015 1,104 words 0 likes 513 comments Read Read

Fish – Now By Prescription

Scott Alexander examines overpriced medical products like Lovaza and Deplin, arguing they serve a purpose in the medical system, but criticizes exorbitant BRCA gene testing prices as harmful.

ssc
Jun 15, 2014 2,213 words 0 likes 90 comments Listen · 16 min Read Read

Links for Octember

A collection of interesting links covering history, science, economics, and culture, with Scott's commentary and observations on each topic.

ssc
Sep 30, 2013 1,631 words 0 likes 44 comments Read Read

Sleep – Now By Prescription

Scott Alexander critiques the medical system's preference for expensive prescription sleep aids like Ramelteon over cheaper alternatives like melatonin, while sharing interesting facts about melatonin's uses.

ssc
Sep 28, 2013 1,316 words 0 likes 49 comments Listen · 11 min Read Read
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