Josh Morrison argues that AI superforecasting could transform FDA drug approval by replacing subjective expert judgment with objective, quantitative predictions about drug safety and efficacy.

Scott argues that California's proposed billionaire tax is actually an extortion scheme by SEIU, which has a history of proposing destructive ballot initiatives and withdrawing them in exchange for concessions.

A monthly collection of diverse links covering AI developments and regulation, COVID origins debates, healthcare policy, cultural phenomena, scientific research, and internet curiosities, maintaining Scott's characteristic blend of serious analysis and entertaining observations.

Scott Alexander and 1DaySooner outline potential positive health policy initiatives that could emerge under three key Trump administration health appointees: Jim O'Neill, Marty Makary, and Jay Bhattacharya.

Scott Alexander examines the complexities of abolishing the FDA and proposes more practical alternatives to increase medical innovation while maintaining safeguards.

Scott Alexander summarizes and responds to various comments on his kidney donation post, covering a wide range of related topics and perspectives.

Scott Alexander recounts his experience donating a kidney, from initial motivation to post-surgery recovery, while discussing the broader context of organ donation.

Scott Alexander responds to comments on his post about new telemedicine regulations, addressing various concerns and criticisms raised by readers.

Scott Alexander criticizes new DEA regulations that restrict telemedicine prescriptions for controlled substances, arguing they will harm patients and legitimate practices while failing to prevent abuse.

Scott Alexander compiles reader comments on healthcare systems in various countries, discussing economics, drug pricing, and personal experiences.

Scott Alexander defends his criticism of the FDA's approval process in the infant fish oil case, arguing that systemic issues cause harmful delays even when the FDA follows its mandate.

Scott Alexander presents numerous examples of how the U.S. employer-provided health insurance system fails even insured, well-off individuals, arguing that almost any alternative system would be better.

Scott Alexander offers various strategies for obtaining affordable mental health care and medication in the US, including discount programs, therapy alternatives, and supplement options.

A collection of interesting links covering medical research, sociology, politics, and technology, with brief commentary on each item.

A diverse collection of links covering current events, scientific studies, and cultural developments, with brief commentary on each story's significance or implications.

Scott Alexander discusses potential Trump administration health-related appointments, focusing on FDA commissioner candidates Jim O'Neill and Balaji Srinivasan, and their potential to implement beneficial reforms.

Scott argues against Vox's proposal for drug price controls, citing studies that such policies would significantly reduce pharmaceutical innovation and potentially cost millions of life-years long-term.

A collection of interesting links spanning drug policy, scientific studies, historical oddities, and current events, with Scott's commentary on each.

A Links post presenting various interesting news and studies from different fields, with brief commentary on each item.

Scott Alexander criticizes the idea that prisons have replaced mental hospitals, arguing for better community and forensic mental health care instead of long-term institutionalization.

A collection of interesting links covering technology, science, economics and society, with Scott's commentary and analysis on each topic.