Scott examines the concept of 'priesthoods' (like medicine and academia) as epistemic communities that maintain high standards through isolation from the public, showing both their strengths and their vulnerability to ideological capture. Longer summary

Scott analyzes how professional 'priesthoods' like medicine and academia function as epistemic communities, maintaining their effectiveness through deliberate isolation from the public and strict internal standards. He explains how their key features - separation from the public, resistance to capitalism, and formal communication norms - help them maintain quality but also make them vulnerable to ideological capture. The post explores how these institutions were particularly susceptible to political capture in recent years, while arguing that despite their flaws, they still serve an important function that would be difficult to replicate. The discussion concludes by questioning how to deal with priesthoods' current state of partial corruption. Shorter summary

Scott Alexander examines how compounding pharmacies are producing cheaper versions of GLP-1 agonist drugs, exploring the economics, safety, and future implications of this practice. Longer summary

Scott Alexander discusses the 'compounding loophole' that allows compounding pharmacies to produce cheaper versions of GLP-1 agonist drugs like semaglutide (Ozempic). He explains how these pharmacies operate, the cost differences, safety concerns, and potential future implications. The post covers the legal basis for this practice during drug shortages, the impact on drug manufacturers like Novo Nordisk, and speculates on what might happen when the shortage ends. Scott also touches on the broader implications for drug pricing and availability. Shorter summary

Scott Alexander presents a diverse collection of 49 links and brief commentaries on various topics, ranging from cultured meat to AI developments and current events. Longer summary

This post is a collection of 49 diverse links and brief commentaries on various topics, including cultured meat, government policies, scientific studies, historical anecdotes, AI developments, and current events. The author, Scott Alexander, provides his thoughts and observations on each item, often with a mix of humor, skepticism, and analysis. The links cover a wide range of subjects from technology and economics to politics and culture, reflecting the broad interests of the blog's readership. Shorter summary

Scott examines data on COVID-19 lockdown effectiveness, finding they likely reduced transmission but at significant costs, with targeted measures being most effective. Longer summary

Scott analyzes the effectiveness of COVID-19 lockdowns, examining data from Sweden, US states, and Europe. He finds that lockdowns likely reduced transmission rates, with targeted measures like school closures being more effective than stay-at-home orders. The analysis suggests lockdowns saved lives but at significant economic and emotional costs, with the cost-effectiveness varying between countries and time periods. Scott concludes that fast, well-targeted lockdowns may have been optimal, but emphasizes the high uncertainty in these estimates. Shorter summary

Scott Alexander investigates the optimal dosage of Lexapro, comparing it to other antidepressants and exploring the reasons behind its effectiveness at lower doses. Longer summary

Scott Alexander explores the question of the right dose for Lexapro (escitalopram), an antidepressant. He examines official recommendations, compares Lexapro to other SSRIs, and investigates why Lexapro might be effective at lower doses. The post delves into studies on antidepressant dosing, the unique properties of Lexapro, and the potential benefits and risks of higher doses. Scott concludes that while there's no strong evidence for high doses of any antidepressant being more effective, prescribing higher doses of Lexapro might be as safe as other SSRIs and potentially more beneficial in some cases. Shorter summary

Scott Alexander discusses various aspects of the COVID-19 pandemic, including strategies, mysteries, controversies, and global impacts. Longer summary

This blog post discusses various aspects of the COVID-19 pandemic, including the 'hammer and dance' strategy, smoking cessation, mysteries surrounding Japan's low case numbers, takeout food safety, ventilator numbers, the UK's policy reversal, density and infection rates, hydroxychloroquine controversy, concerns about developing countries, donation opportunities, cost-benefit analysis of lockdowns, US stimulus bill negotiations, and media coverage of the pandemic across the political spectrum. The post also includes short links to other coronavirus-related news and developments. Shorter summary

Scott shares and comments on a diverse collection of news items and interesting links from March 2014, covering topics from medical advances to political issues and quirky stories. Longer summary

This post is a collection of various links and news items from March 2014. Scott covers a range of topics including medical advances, political issues, social science research, and quirky news stories. He comments on each item, often with a skeptical or humorous tone. The post touches on subjects like fecal transplants, charity effectiveness, SAT preparation myths, prediction markets, and genetic research. Scott also discusses some sociological theories and shares interesting statistics and studies. Shorter summary