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25 posts found
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Jun 16, 2026
acx
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45 min 6,939 words 115 comments 189 likes podcast (38 min)
A replication of a 2023 neuroscience study on brain entrainment and learning found that the original effect likely doesn't exist, revealing how the study obscured key issues through statistical averaging and highlighting how AI tools are democratizing scientific scrutiny. Longer summary
Sasha Putilin received an ACX grant to replicate a 2023 study claiming that flickering lights synchronized to individual brain rhythms could boost learning speed threefold. The $32,000 replication with 12 participants (versus 80 in the original) found no such effect. Upon examining the original data more closely, Putilin discovered the apparent effect was driven entirely by a few participants with large negative learning rates (getting worse over time) who happened to all be in one experimental group. The original study had obscured this pattern by presenting averaged data rather than individual results. Putilin argues this exemplifies 'cargo-cult statistics' where researchers mechanically apply statistical rituals without critically examining underlying data. The post concludes by suggesting AI tools are democratizing meta-science, enabling anyone to audit published research that previously required expert-level effort. Shorter summary
Aug 31, 2023
acx
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23 min 3,462 words 706 comments 280 likes podcast (21 min)
Scott Alexander defends the concept of automaticity in psychology, arguing that core cognitive biases and priming effects are real, while acknowledging some claims have been overstated. Longer summary
Scott Alexander responds to a critique of automaticity in psychology, arguing that while some claims about cognitive biases and priming have been overstated, the core concepts are real and well-replicated. He provides examples of cognitive biases, priming effects, and nudges that have strong evidence behind them. Scott compares cognitive biases to optical illusions - real phenomena that affect our perception, but not in ways that make us completely helpless. He argues that automaticity is actually a very old idea about human nature, found in various philosophical and religious traditions. While we shouldn't see ourselves as completely controlled by unconscious forces, Scott suggests that accepting some level of automaticity in our cognition is both realistic and not necessarily problematic. Shorter summary
May 11, 2023
acx
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46 min 7,069 words 101 comments 59 likes podcast (38 min)
Scott Alexander addresses feedback on his post about bisexuality and Long COVID, discussing alternative explanations and defending his methodology. Longer summary
Scott Alexander responds to comments on his previous post about the correlation between bisexuality and Long COVID. He addresses alternative explanations, concerns about sample size and methodology, the nature of psychosomatic illness, and various other points raised by readers. Scott maintains that while the association exists in the data, the cause remains uncertain and could be due to various factors including response patterns, biological differences, or a combination of organic and psychosomatic elements. Shorter summary
Jul 15, 2022
acx
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80 min 12,330 words 314 comments 126 likes podcast (75 min)
The review critiques Haidt's 'The Righteous Mind', praising its contributions while highlighting flaws in its moral foundations theory and political predictions. Longer summary
This review critiques Jonathan Haidt's 'The Righteous Mind', praising its contributions to moral psychology while highlighting significant flaws. The reviewer appreciates Haidt's defense of group selection and moral intuitionism but criticizes his confusion between normative and descriptive claims. The review argues that Haidt's moral foundations theory fails to predict political alignments just a decade after publication, suggesting that political tribalism drives moral intuitions rather than vice versa. Despite these criticisms, the reviewer recommends the book for its thought-provoking nature and its role in advancing empiricism in social science. Shorter summary
Aug 30, 2021
acx
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47 min 7,248 words 361 comments 116 likes podcast (46 min)
Scott Alexander argues that despite some replication failures, the core of behavioral economics remains valid and valuable, with the field continuing to evolve and refine its understanding of human decision-making. Longer summary
Scott Alexander responds to Jason Hreha's article claiming the 'death of behavioral economics'. He argues that while some studies have failed to replicate, the core insights of behavioral economics remain valid. Scott examines the historical origins of loss aversion, discusses recent debates about its existence, and argues that even small effect sizes can be valuable at scale. He concludes that behavioral economics as a field is generally healthy, continuing to investigate and refine our understanding of human decision-making, though specific paradigms may evolve over time. Shorter summary
Jan 08, 2020
ssc
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32 min 4,854 words 166 comments podcast (29 min)
Scott Alexander reviews his intellectual progress in the 2010s across various fields, crediting his blog for accelerating learning. Longer summary
Scott Alexander reflects on the intellectual progress he made in the 2010s, largely tracked through his blog posts. He discusses major updates in his understanding of topics like predictive coding theory, psychedelics, mental health, SSRIs, genetics, willpower, nutrition, x-risk, AI, scientific progress, cost disease, the replication crisis, placebo effect, ethics, politics, cultural evolution, social justice, game theory, and enlightenment. He notes that while some were major shifts in position, many represent 'deconfusion' - gaining a better map of the problem space. Scott credits his blog and reader interactions for accelerating his learning in the latter half of the decade. Shorter summary
Sep 09, 2019
ssc
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5 min 671 words 21 comments podcast (6 min)
Scott Alexander partially retracts and corrects his previous findings on age gaps and birth order effects after errors were identified in his analysis. Longer summary
Scott Alexander partially retracts his previous findings on age gaps and birth order effects. He acknowledges that Bucky, a Less Wrong user, found errors in his analysis of SSC survey data. While the original conclusion about firstborn children being overrepresented in high-openness STEM types remains valid, the specific findings about age gaps were partially incorrect. Scott explains the errors, presents Bucky's corrected analysis, and discusses the implications. He emphasizes the importance of data transparency and encourages readers to double-check his work. Shorter summary
May 07, 2019
ssc
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22 min 3,284 words 155 comments podcast (24 min)
Scott examines how the 5-HTTLPR gene was wrongly linked to depression for years, discussing the implications for psychiatric research and genetic testing products. Longer summary
This post discusses the history and eventual debunking of the 5-HTTLPR gene's supposed role in depression. Initially, numerous studies claimed to find links between 5-HTTLPR and various mental health conditions, interactions with stress, and even antidepressant efficacy. However, a recent large-scale study by Border et al. found no evidence for these claims, suggesting that hundreds of previous studies were likely false positives. The post explores the implications of this finding, including concerns about the reliability of psychiatric research, the tendency for studies to reinforce existing beliefs, and the questionable validity of pharmacogenomic testing products that rely on genes like 5-HTTLPR. Shorter summary
Apr 04, 2018
ssc
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25 min 3,742 words 99 comments podcast (29 min)
The post reviews research on adult neurogenesis, initially presenting evidence for its existence and importance, then reveals a new study suggesting it doesn't occur in humans, examining the implications of this potential field-wide error. Longer summary
This post reviews the literature on adult neurogenesis, initially presenting numerous studies that claimed to find evidence for the generation of new neurons in adult human brains. These studies linked adult neurogenesis to various aspects of brain function, including memory, learning, and depression. However, the post then reveals a new study suggesting that adult neurogenesis doesn't actually occur in humans, or is so rare as to be insignificant. The author examines how this field-wide error could have occurred, discussing the extrapolation of rat studies to humans and the role of confirmation bias. The post ends by reflecting on the implications of this for scientific research and the replication crisis. Shorter summary
Apr 02, 2018
ssc
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10 min 1,521 words 146 comments podcast (14 min)
Scott Alexander critically examines conflicting studies on Amish happiness levels, finding the research too unreliable to draw firm conclusions. Longer summary
Scott Alexander examines conflicting claims about Amish happiness levels compared to modern societies and billionaires. He finds significant inconsistencies and methodological issues in the various studies, making it difficult to draw firm conclusions. The post highlights problems with data interpretation, study replication, and potential confounding factors. Scott emphasizes the unreliability of these early happiness studies, which predate improvements brought by the replication crisis in social science. He concludes that the research is not rigorous enough to make definitive statements about Amish happiness levels relative to other groups. Shorter summary
Jan 08, 2018
ssc
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12 min 1,799 words 401 comments podcast (15 min)
Scott Alexander presents survey data showing a strong overrepresentation of oldest siblings among his blog readers, challenging the view that birth order effects are negligible. Longer summary
Scott Alexander challenges the mainstream view that birth order effects are negligible, presenting data from his blog survey that shows a strong tendency for oldest children to be overrepresented among his readers. He finds that in families of two children, 71.4% of respondents were the older sibling, with similar patterns in larger families. While he couldn't fully replicate previous studies' findings on IQ differences, he did find a significant difference in Openness to Experience. Scott suggests that birth order may have a stronger effect on intellectual curiosity than previously thought, which could explain the skewed ratios in certain communities. He calls for further research to understand the mechanisms behind this effect and its potential implications. Shorter summary
Apr 17, 2017
ssc
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40 min 6,075 words 609 comments
Scott Alexander examines his evolving view on scientific consensus, realizing it's more reliable and self-correcting than he previously thought. Longer summary
Scott Alexander reflects on his changing perspective towards scientific consensus, sharing personal experiences where he initially believed he was defying consensus but later discovered that the scientific community was often ahead of or aligned with his views. He discusses examples from various fields including the replication crisis, nutrition science, social justice issues, and AI risk. Alexander concludes that scientific consensus, while not perfect, is remarkably effective and trustworthy, often self-correcting within a decade of new evidence emerging. Shorter summary
Feb 27, 2017
ssc
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23 min 3,526 words 211 comments
Scott Alexander examines a failed replication of a study claiming analytical thinking promotes religious disbelief, and discusses the broader implications for understanding the relationship between thinking styles and religious belief. Longer summary
Scott Alexander reviews a study by Gervais and Norenzayan (G&N) that claimed analytical thinking promotes religious disbelief, and its subsequent failed replication attempts. The original study consisted of five experiments, including priming participants with images or word tasks before assessing their religious beliefs. The Reproducibility Project's replication of two of these experiments failed to find the same effects. Scott discusses the implications of this failure, noting that even studies that seem well-designed can fail to replicate. He then examines a meta-analysis by Pennycook et al. that found a small but consistent correlation between analytical thinking and irreligiosity across multiple studies. Scott concludes by summarizing key takeaways about the relationship between analytical thinking, IQ, and religious belief, as well as lessons about the replicability of psychological studies. Shorter summary
Jan 14, 2017
ssc
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10 min 1,505 words 64 comments
Scott Alexander critiques a Buzzfeed article skeptical of growth mindset research, arguing that while skepticism is warranted, more robust evidence is needed to disprove the theory. Longer summary
Scott Alexander discusses a Buzzfeed article criticizing growth mindset research, particularly the work of Carol Dweck. While acknowledging the hype around growth mindset and his own skepticism, Scott argues that the article's critique is not sufficiently robust. He points out that despite the reasons to be suspicious, the growth mindset studies have shown strong results. Scott identifies three main criticisms in the Buzzfeed piece but finds them lacking in strength to fully debunk the theory. He emphasizes the importance of thorough, evidence-based criticism rather than relying on intuition or weak arguments. Scott warns against dismissing potentially valid research too quickly, using an analogy to climate change denial tactics. He concludes by calling for more rigorous efforts to disprove growth mindset if it is indeed flawed. Shorter summary
Oct 04, 2016
ssc
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13 min 1,888 words 221 comments
Scott shares various interesting news items and studies spanning history, science, politics, and technology, with commentary on each item's significance or irony. Longer summary
A diverse collection of interesting links and news items covering various topics. The post includes historical curiosities (like Merv being the world's largest city), scientific research (including studies about genetic risk for sugar consumption and school effects), political developments (like Steve Bannon's profile and Trump's microphone issues), technology news (AI partnership between tech giants), and social issues (discrimination studies and immigration effects). The post maintains a light, sometimes humorous tone while discussing serious subjects, often adding ironic observations about how things work. Shorter summary
Aug 26, 2016
ssc
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14 min 2,074 words 624 comments
A link roundup post covering various topics from video games to scientific studies, with Scott's commentary on each news item or piece of research. Longer summary
A collection of interesting links covering diverse topics including scientific studies (Tylenol and ADHD, obesity genetics), current events (self-driving Uber cars, DoJ ending private prisons), cultural observations, and historical curiosities. Scott provides brief commentary on each link, often critiquing methodology of studies or pointing out interesting implications. The post has a lighter tone when discussing oddities like torpedo juice or Desert Bus, but becomes more analytical when examining research claims or policy changes. Shorter summary
Aug 25, 2016
ssc
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14 min 2,098 words 291 comments
Scott examines psychological phenomena attributed to the unconscious mind, noting many have failed to replicate, and suggests a shift away from the power of the unconscious in psychological research. Longer summary
This post explores the concept of 'voodoo death' and its parallels in psychology, suggesting that many psychological phenomena previously attributed to the power of the unconscious mind may be less significant than once thought. Scott examines several examples, including the placebo effect, stereotype threat, self-esteem, and social priming, noting that many of these effects have failed to replicate in recent studies. He proposes a pattern of shifting away from the power of the unconscious in psychological research, while acknowledging the limitations of his analysis. The post concludes by considering the implications for Freudian psychology and suggesting a need to reevaluate our understanding of the unconscious mind. Shorter summary
Jun 07, 2016
ssc
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11 min 1,657 words 94 comments
Scott examines new research on ketamine's antidepressant effects and its implications for understanding depression and evaluating psychiatric literature. Longer summary
This post discusses new research on ketamine's antidepressant effects, which suggests they are caused by a metabolite rather than ketamine itself. The author examines how this finding impacts previous research and understanding of ketamine's mechanism of action. He reviews studies on NMDA antagonists and finds mixed results, with some potential bias when conflicts of interest are present. The post concludes by reflecting on the implications for trusting psychiatric literature, especially in cases with conflicts of interest. Shorter summary
Apr 15, 2016
ssc
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17 min 2,623 words 393 comments
A links roundup examining various scientific studies, social developments, and historical findings, with a particular focus on recent research about confounding variables and replication issues in science. Longer summary
This is an extensive links post covering various scientific studies, news items, and interesting facts. Scott discusses several studies about confounding variables and replication in science, historical findings about ancient civilizations, new research on topics ranging from climate change to criminology, and various social and political developments. The post starts with methodological concerns in science, moves through various research findings and historical tidbits, and ends with news about ongoing projects and obituaries. The tone is analytical but casual, with Scott often adding his own commentary and pointing out interesting implications or contradictions. Shorter summary
Mar 09, 2016
ssc
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20 min 3,099 words 52 comments
A links roundup post covering recent developments in science, medicine, psychology and politics, with particular focus on research replication issues and the 2016 election season. Longer summary
This is a links roundup post covering various recent research findings, news, and developments. It covers topics from toxoplasma research, drug trials, and scientific replication crises to politics and social issues. The post discusses several important developments in psychology including failed replications of established theories like ego depletion, updates on clinical trials and drug research, and various political developments around the 2016 election season. It maintains a light tone while discussing serious academic and scientific topics, including several meta-analyses and study critiques. Shorter summary
Sep 05, 2015
ssc
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13 min 1,866 words 318 comments
Scott Alexander argues that psychology is indeed in crisis, contrary to a New York Times article's claim, due to issues like publication bias and low replication rates. Longer summary
Scott Alexander critiques a New York Times article claiming psychology is not in crisis despite low replication rates. He argues that the article ignores publication bias, experimenter effects, and low base rates of true hypotheses. Scott contends that even if failed replications are due to different conditions, this still represents a crisis as it undermines the practical utility of psychological findings. He suggests that while we can't investigate every failed replication, studying some might reveal why replication issues keep occurring in psychology. Shorter summary
May 08, 2015
ssc
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11 min 1,617 words 503 comments
Scott shares and comments on various links covering science, politics, and culture, with topics ranging from automation's effect on employment to psychology's replication crisis. Longer summary
This is a collection of interesting links and brief commentaries by Scott Alexander. He covers a wide range of topics including scientific studies, current events, and cultural phenomena. Notable items include studies about employment and automation, discrimination research methodology, problems with student course evaluations, and psychology's reproducibility crisis. The post also includes quirky items like Dutch swearing customs and unusual products, maintaining Scott's characteristic mix of serious analysis and lighter observations. Shorter summary
Apr 15, 2015
ssc
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20 min 3,015 words 291 comments
Scott Alexander analyzes two conflicting studies on gender bias in STEM hiring, exploring reasons for their contradictory results and the challenges in reaching a definitive conclusion. Longer summary
Scott Alexander discusses two contradictory studies on gender bias in STEM hiring, one showing bias against women and another showing bias in favor of women. He explores possible reasons for the discrepancy, including differences in methodology and potential experimenter bias. The post highlights the difficulty in reaching a definitive conclusion on this issue despite its importance and the resources dedicated to studying it. Scott suggests that the conflicting results might be due to subtle experimenter effects and proposes a joint study by both teams as a potential solution. Shorter summary
Apr 28, 2014
ssc
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33 min 4,983 words 197 comments podcast (38 min)
Scott Alexander critiques a meta-analysis supporting psychic phenomena to illustrate flaws in scientific methodology and meta-analysis. Longer summary
Scott Alexander examines a meta-analysis by Daryl Bem that claims to provide strong evidence for psychic phenomena (psi). While Bem's analysis follows many best practices for scientific rigor, Alexander argues it likely suffers from experimenter effects and other biases that can produce false positive results. He uses this to illustrate broader issues with the scientific method and meta-analysis, concluding that even seemingly rigorous studies and meta-analyses can produce incorrect conclusions. This challenges the idea that scientific consensus and meta-analysis are the highest forms of evidence. Shorter summary
Feb 25, 2014
ssc
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3 min 456 words 16 comments
Scott Alexander humorously proposes a reality TV show called 'Replication Lab!' to address the crisis of replication in psychology by making the process more entertaining. Longer summary
Scott Alexander proposes a humorous solution to the crisis of replication in psychology: a reality TV show called 'Replication Lab!'. The show would attempt to replicate famous experiments each week, turning the unglamorous task of replication into entertaining television. The post describes a hypothetical episode, complete with dramatic tension, human interest stories, and the potential for career-ruining failures to replicate. The satirical proposal aims to make replication more appealing and address the serious issue of unreliable research in a lighthearted way. Shorter summary
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