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meta-analysis (18)
study critique (270)
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study critique (270)
book review (221)
AI (112)
economics (105)
effective altruism (105)
education (93)
creative writing (91)
debate (89)
forecasting (89)
politics (89)
prediction markets (88)
science (85)
AI safety (79)
media criticism (76)
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psychiatry (73)
psychology (72)
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18 posts
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Never Cross a River Four Feet Deep on Average

A replication of a 2023 neuroscience study on brain entrainment and learning found that the original effect likely doesn't exist, revealing how the study obscured key issues through statistical averaging and highlighting how AI tools are democratizing scientific scrutiny.

acx
Jun 16, 2026 6,939 words 190 likes 115 comments Listen · 38 min Read Read Opened Opened

Response To Alexandros Contra Me On Ivermectin

Scott Alexander responds to critiques of his 2021 ivermectin analysis, acknowledging some errors but maintaining his conclusion that ivermectin likely doesn't work for COVID-19.

acx
Feb 1, 2023 13,335 words 108 likes 308 comments Listen · 79 min Read Read Opened Opened

Ivermectin: Much More Than You Wanted To Know

Scott Alexander analyzes ivermectin studies for COVID-19, finding most positive results likely due to methodological flaws, fraud, or confounding by parasitic infections.

acx
Nov 17, 2021 16,786 words 445 likes 2,113 comments Listen · 128 min Read Read Opened Opened

Book Review: Arabian Nights

Scott reviews 'Arabian Nights', exploring its themes, fantastical elements, and proposing a meta-interpretation of Scheherazade's storytelling strategy.

acx
May 24, 2021 4,617 words 260 likes 320 comments Listen · 28 min Read Read Opened Opened

Preschool: Much More Than You Wanted To Know

Scott Alexander critically examines studies on preschool effects, finding mixed and inconsistent evidence for long-term benefits.

ssc
Nov 13, 2018 5,299 words 0 likes 164 comments Listen · 38 min Read Read Opened Opened

SSRIs: An Update

Scott Alexander revisits his stance on SSRIs, discussing new meta-analyses, broader trends in psychiatric medication efficacy, and potential explanations for the discrepancy between statistical and clinical observations.

ssc
Nov 7, 2018 1,642 words 0 likes 74 comments Listen · 13 min Read Read Opened Opened

SSC Journal Club: Cipriani On Antidepressants

Scott Alexander critically examines a major meta-analysis on antidepressant efficacy, noting potential biases and comparing its surprising drug rankings to his own previous analysis.

ssc
Feb 26, 2018 2,764 words 0 likes 45 comments Listen · 21 min Read Read Opened Opened

Contra Grant On Exaggerated Differences

Scott Alexander critiques Adam Grant's article on gender differences in tech, arguing Grant misrepresents evidence and ignores key factors like innate interest differences between men and women.

ssc
Aug 7, 2017 6,903 words 0 likes 3 comments Listen · 69 min Read Read Opened Opened

SSC Journal Club: Analytical Thinking Style And Religion

Scott Alexander examines a failed replication of a study claiming analytical thinking promotes religious disbelief, and discusses the broader implications for understanding the relationship between thinking styles and religious belief.

ssc
Feb 27, 2017 3,531 words 0 likes 211 comments Read Read Opened Opened

Schizophrenia: No Smoking Gun

The post explores the complex relationship between smoking and schizophrenia, critiquing conflicting studies and cautioning against hasty conclusions about nicotine's effects on schizophrenia risk.

ssc
Jan 11, 2016 1,679 words 0 likes 264 comments Read Read Opened Opened

Guns and States 2: Son of a Gun

Scott Alexander offers follow-up insights on his guns and states analysis, addressing cultural factors, rape correlations, replication issues, and the complexity of gun control debates.

ssc
Jan 10, 2016 1,020 words 0 likes 507 comments Read Read Opened Opened

Trouble Walking Down The Hallway

Scott Alexander analyzes two conflicting studies on gender bias in STEM hiring, exploring reasons for their contradictory results and the challenges in reaching a definitive conclusion.

ssc
Apr 15, 2015 3,019 words 0 likes 291 comments Read Read Opened Opened

Beware The Man Of One Study

Scott Alexander cautions against basing opinions on limited research, using examples from medicine and economics to show how cherry-picking studies can lead to opposing conclusions.

ssc
Dec 12, 2014 2,880 words 0 likes 270 comments Listen · 22 min Read Read Opened Opened

The Dark Side Of Divorce

The author revisits their belief in genetic determinism, presenting evidence that environmental factors, especially in divorce, have significant non-genetic effects on children's outcomes.

ssc
Nov 14, 2014 1,846 words 0 likes 205 comments Read Read Opened Opened

Links For May 2014

A monthly links post collecting and commenting on various interesting articles and studies from around the web, ranging from scientific research to philosophy to economics.

ssc
May 1, 2014 2,117 words 0 likes 150 comments Read Read Opened Opened

The Control Group Is Out Of Control

Scott Alexander critiques a meta-analysis supporting psychic phenomena to illustrate flaws in scientific methodology and meta-analysis.

ssc
Apr 28, 2014 4,998 words 0 likes 197 comments Listen · 38 min Read Read Opened Opened

Beware Mass-Produced Medical Recommendations

Scott Alexander critiques mass-produced medical recommendations, showing how they can oversimplify or misrepresent scientific evidence using vitamin D and niacin as examples.

ssc
Jan 25, 2014 2,816 words 0 likes 58 comments Read Read Opened Opened

90% of all claims about the problems with medical studies are wrong

Scott Alexander examines the claim that '90% of medical research is false', arguing it's an exaggeration while acknowledging real issues in the field.

ssc
Feb 17, 2013 3,699 words 0 likes 26 comments Read Read Opened Opened
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