Scott defends psychology against broad dismissals by showing that the replication crisis primarily affected only social priming within social psychology, while the vast majority of the field consists of solid, replicable research across many subdisciplines.

A review of 'Great and Desperate Cures' by Elliot Valenstein, which examines the history of lobotomy and psychosurgery, explaining how tens of thousands of patients underwent dangerous brain operations from the 1930s-1950s despite poor evidence of effectiveness.

A deep dive into the Book of Abraham, focusing on how Joseph Smith's translations of Egyptian papyri were definitively proven false by Egyptologists, yet Mormonism continues to thrive—raising questions about whether instrumental rationality trumps epistemic rationality.

A replication of a 2023 neuroscience study on brain entrainment and learning found that the original effect likely doesn't exist, revealing how the study obscured key issues through statistical averaging and highlighting how AI tools are democratizing scientific scrutiny.

Scott reviews the state of prediction markets after explosive growth, finding that most volume is degenerate sports gambling rather than useful forecasting, and proposes both technical solutions and two potential futures for the field.

A detailed insider look at Phase I clinical drug trials, revealing how the system's structure encourages participants to routinely lie about their medical history and symptoms to continue participating.

A guest post defending the amyloid hypothesis of Alzheimer's disease, explaining why amyloid is likely the root cause despite recent criticism and discussing why early treatments have only been partially effective.

Scott analyzes the sudden emergence of commercial trait-based embryo selection services, discussing both the scientific validity and ethical implications of selecting embryos for health outcomes, intelligence, and physical traits.

A detailed review of a 1995 paper introducing the PDAPP mouse model for Alzheimer's disease, examining how its limitations were overlooked and shaped decades of potentially misguided Alzheimer's research.

Scott presents evidence that COVID-19 did kill approximately 1.2 million Americans, addressing skeptics by analyzing excess death data and addressing common counterarguments.

Scott Alexander criticizes Tyler Cowen and others for misrepresenting USAID's funding model, explaining how regranting through other charities is both necessary and effective despite seeming inefficient to outsiders.

Scott critiques the phrase 'the purpose of a system is what it does' by showing how it confuses outcomes with intentions and leads to absurd or paranoid conclusions.

Scott Alexander criticizes the misleading use of 'no evidence' in science communication and suggests more nuanced alternatives.

The review examines Nicholson Baker's 'Double Fold', a critique of libraries replacing original books and newspapers with inferior microfilm copies.

Scott examines how the 5-HTTLPR gene was wrongly linked to depression for years, discussing the implications for psychiatric research and genetic testing products.

Scott Alexander criticizes Ted Chiang's article that compares AI risk to capitalism, arguing that the analogy is flawed and the reasoning behind it is unsound.

A collection of interesting links covering various topics from scientific studies, social issues, and current events, including problems with brain imaging studies, AI safety developments, and surprising research findings.

A collection of interesting links and studies on various topics, from bad statistics and media coverage to technological progress and scientific discoveries, with commentary from Scott Alexander.

A links roundup examining various scientific studies, social developments, and historical findings, with a particular focus on recent research about confounding variables and replication issues in science.

A links roundup post covering recent developments in science, medicine, psychology and politics, with particular focus on research replication issues and the 2016 election season.

Scott Alexander criticizes websites that misleadingly suggest drug side effects by scraping FDA data, potentially causing patients to stop taking necessary medications.

Scott Alexander dissects and criticizes Breitbart's misleading use of statistics about illegal immigrant crime, emphasizing the need for better understanding and interpretation of data in political debates.

A collection of interesting links covering recent research, controversies, and developments across various fields including science, economics, politics and sociology, with Scott's brief commentary on each.

A collection of interesting links covering science, economics, and culture, with key stories about psychology study replication failures and various scientific findings.

Scott shares and comments on various news articles and studies, covering topics from police tactics and Trump's campaign to behavioral genetics and dietary research.