Scott Alexander presents 51 links covering AI progress and safety, political developments, scientific research, cultural oddities, and ongoing philosophical debates about miracles and education reform.

Scott explores the 'missing heritability' problem in genetics, where twin studies show traits like IQ and educational attainment are highly heritable but newer genomic methods find much lower heritability, analyzing various potential explanations for this discrepancy.

A diverse collection of news items, studies, and interesting facts from November 2024, covering topics from scientific discoveries to cultural phenomena.

Scott Alexander responds to Robin Hanson's reply on medical effectiveness, clarifying interpretations and reiterating arguments about the limitations of insurance experiments in evaluating medical care.

A collection of 47 diverse links and news items covering topics from religious practices to AI developments, with brief commentary on many items.

Scott Alexander examines a study challenging ketamine's effectiveness as an antidepressant, discussing potential confounding factors and maintaining his belief in ketamine's utility despite the study's results.

Scott Alexander examines the 'canalization' theory in computational psychiatry and its refinement through deep learning concepts in the Deep CANAL model.

The post examines prediction markets for Trump's 2024 chances, Musk's Twitter deal, and the impact of the Dobbs decision, while also discussing new forecasting initiatives and other current events.

Scott Alexander critiques Ben Hoffman's arguments about Vitamin D dosing, maintaining that it is primarily a bone-related chemical with limited evidence for other benefits.

Scott Alexander shares 33 diverse links on topics ranging from history and science to technology and politics, offering brief summaries and commentary on each.

Scott Alexander argues that doctors should prescribe fluvoxamine for COVID-19 despite FDA inaction, urging them to overcome discomfort with off-label use when evidence supports it.

Scott Alexander shares 34 varied links and pieces of information on topics including science, history, politics, and technology, with brief commentary on many items.

Scott Alexander analyzes ivermectin studies for COVID-19, finding most positive results likely due to methodological flaws, fraud, or confounding by parasitic infections.

Scott Alexander examines the current research on Long COVID, analyzing its prevalence, symptoms, and potential impacts to assess personal risk and societal implications.

Scott examines data on COVID-19 lockdown effectiveness, finding they likely reduced transmission but at significant costs, with targeted measures being most effective.

Scott Alexander examines two cases of multiple hypothesis testing problems in medical and social science research, highlighting the complexities in interpreting results.

Scott Alexander critically evaluates the evidence for Vitamin D's role in COVID-19 prevention and treatment, ultimately leaning towards skepticism while acknowledging the low risk of supplementation.

Scott Alexander provides updates and speculations on various aspects of the COVID-19 pandemic, including case estimates, strategies, medical issues, and societal responses.