Scott Alexander provides a comprehensive guide on ketamine as a depression treatment, covering administration methods, effectiveness, safety, dosage, and potential side effects.

The review analyzes 'Plagues and Peoples' by William H. McNeill, which presents human history as shaped by the interaction between humans, microparasites, and societal structures.

Scott Alexander presents a detailed guide on depression, covering its causes, symptoms, and various treatment options, including lifestyle changes, therapies, medications, and other interventions.

Scott Alexander proposes a Bayesian theory of willpower as a process of weighing evidence from different mental processes to determine actions.

Scott Alexander reviews 'Against The Grain', which argues that early grain agriculture and state formation were detrimental to human welfare and mainly benefited emerging state powers.

Scott Alexander explores a theory suggesting that complex features of human biology evolved as defenses against parasite manipulation, discussing its implications for understanding psychiatric medications and biological complexity.

Scott Alexander reviews 'Zero To One' by Peter Thiel, discussing its advice on creating monopolies, believing in secrets, and embracing definite optimism for successful startups.

Scott Alexander presents a diverse collection of links and brief commentary on topics ranging from historical anecdotes to recent scientific studies and political developments.

Scott proposes that value differences arise from people crystallizing heuristics at different levels, rather than from fundamental, incomprehensible differences in values.

The post reviews research on adult neurogenesis, initially presenting evidence for its existence and importance, then reveals a new study suggesting it doesn't occur in humans, examining the implications of this potential field-wide error.

Scott Alexander critically examines a major meta-analysis on antidepressant efficacy, noting potential biases and comparing its surprising drug rankings to his own previous analysis.

Scott Alexander reviews Foucault's 'Madness and Civilization', examining its controversial historical analysis of societal attitudes towards mental illness.

Scott Alexander explores why recreational drugs like ketamine and MDMA have shown more promise in treating mental health conditions than intentionally developed pharmaceuticals, suggesting a new direction for drug research.

A diverse collection of links covering current events, scientific studies, and cultural developments, with brief commentary on each story's significance or implications.

A links roundup examining various scientific studies, social developments, and historical findings, with a particular focus on recent research about confounding variables and replication issues in science.

A links roundup post covering recent developments in science, medicine, psychology and politics, with particular focus on research replication issues and the 2016 election season.

A curated collection of interesting links covering academic debates, cultural issues, economics, and scientific discoveries from around the web.

A collection of interesting links spanning topics from CRISPR technology to economic studies, with Scott's commentary on each item.

Scott Alexander defends Less Wrong and Eliezer Yudkowsky against accusations of being anti-scientific, arguing that developing rational thinking skills beyond traditional scientific methods is valuable and necessary.

Scott examines five potential mechanisms of cultural evolution, discussing their strengths and limitations, and concludes that they don't strongly justify preserving specific cultural features.

A collection of interesting links covering topics from science and politics to economics and culture, with commentary on each item.

A collection of interesting links from September 2014 covering scientific research, social issues, and curiosities, with commentary from Scott Alexander.

Scott Alexander analyzes Moloch as a metaphor for destructive societal coordination problems, using various examples to show how competing incentives can lead to negative outcomes.

Scott analyzes various criticisms of antidepressants, concluding they have modest but real benefits over placebo, with important considerations about side effects and efficacy.

Scott Alexander examines his sudden shift towards conservatism, proposing it may be part of a broader trend of intellectuals differentiating themselves from mainstream leftism.