Scott Alexander responds to comments on his COVID-19 origins debate post, addressing criticisms and maintaining his support for the zoonosis theory.

Scott Alexander argues that schizophrenia should be described as predominantly genetic, addressing counterarguments and emphasizing the importance of this perspective for prevention strategies.

Scott Alexander addresses feedback on his post about bisexuality and Long COVID, discussing alternative explanations and defending his methodology.

Scott Alexander examines obscure pregnancy interventions that may improve child outcomes, rating them by evidence quality and potential impact.

Scott Alexander examines Zulresso and Zuranolone, two neurosteroid drugs for postpartum depression, discussing their efficacy, challenges, and potential future applications.

Scott Alexander responds to comments on his ivermectin article, discussing criticisms, the worms hypothesis, vaccine skepticism, and journalism quality.

Scott Alexander analyzes ivermectin studies for COVID-19, finding most positive results likely due to methodological flaws, fraud, or confounding by parasitic infections.

Scott investigates the claim that cold-related deaths account for 10% of global mortality, exploring various factors and potential impacts of global warming on death rates.

Scott Alexander presents a detailed guide on depression, covering its causes, symptoms, and various treatment options, including lifestyle changes, therapies, medications, and other interventions.

Scott Alexander investigates the optimal dosage of Lexapro, comparing it to other antidepressants and exploring the reasons behind its effectiveness at lower doses.

Scott Alexander analyzes the PANDA Study, a large real-world antidepressant trial, discussing its methodology, results, and implications for understanding antidepressant efficacy.

Scott Alexander reviews evidence on face mask effectiveness against coronavirus, concluding they likely offer some protection despite CDC recommendations against general public use.

Scott Alexander reviews his intellectual progress in the 2010s across various fields, crediting his blog for accelerating learning.

This post examines the pros and cons of using gene editing technologies in humans, discussing scientific, medical, and ethical considerations.

A diverse collection of links covering technology, science, economics, politics, and culture, including critiques of studies, interesting scientific findings, and current events.

Scott Alexander shares a diverse collection of links covering AI, economics, politics, science, and culture, offering brief comments and insights on each topic.

Scott Alexander critically examines a major meta-analysis on antidepressant efficacy, noting potential biases and comparing its surprising drug rankings to his own previous analysis.

A collection of interesting links covering science, technology, culture, and economics, including updates on DNA malware, AI gaming, prison censorship, and various scientific studies.

Scott examines the phenomenon of Hungarian scientific geniuses in the early 20th century, attributing it to a high concentration of high-IQ Ashkenazi Jews in Budapest rather than exceptional education.

Scott Alexander shares a collection of interesting links and studies on various topics, including scientific research, cultural observations, and current events, with brief commentary on each.

The post explores the complex relationship between smoking and schizophrenia, critiquing conflicting studies and cautioning against hasty conclusions about nicotine's effects on schizophrenia risk.

Scott Alexander critiques mass-produced medical recommendations, showing how they can oversimplify or misrepresent scientific evidence using vitamin D and niacin as examples.

Scott Alexander presents a roundup of recent medical and psychological studies, covering topics from UV light exposure to belief in science during stress.