The post challenges the notion that effect sizes below 0.50 for medications are clinically insignificant, using antidepressants as a case study and comparing them to other common drugs. Longer summary

This post discusses the interpretation of effect sizes in medical studies, particularly for antidepressants. It challenges the common notion that effect sizes below 0.50 are clinically insignificant. The author presents a Danish study that simulates various hypothetical medications, showing that even drugs that cure or significantly improve depression in a large percentage of patients might not meet traditional effect size thresholds. The post explains why these thresholds might be unrealistic due to factors like the placebo effect, high standard deviations in placebo groups, and patient dropouts. It also compares antidepressant effect sizes to those of other widely accepted medications, concluding that many common drugs would be considered 'clinically insignificant' by strict effect size standards. The author suggests that claims about 'meaningless effect sizes' should be given less weight compared to other evidence, such as clinical experience. Shorter summary

Scott Alexander shares 40 diverse and intriguing links and news items from September 2022, covering topics from AI advancements to political analysis and cultural observations. Longer summary

Scott Alexander presents a collection of 40 interesting links and news items from September 2022. The topics range from AI developments and their implications, to political analysis, scientific discoveries, and cultural observations. He covers subjects like image generation AI, conspiracy theories, the political situation in South Africa, nuclear power in California, and language models' capabilities. The post also includes personal anecdotes, book reviews, and interesting statistical findings. Shorter summary

Scott Alexander provides updates and speculations on various aspects of the COVID-19 pandemic, including case estimates, strategies, medical issues, and societal responses. Longer summary

This blog post provides updates and speculations on various aspects of the COVID-19 pandemic. It covers topics such as estimating the true number of cases, the lack of a clear endgame strategy, the effectiveness of 'flattening the curve', differentiating COVID-19 from flu symptoms, the use of anti-inflammatory drugs, ventilator shortages, disease seasonality, the need for better data, and the Bay Area's response to the crisis. The post also includes short links to other coronavirus-related news and observations. Shorter summary

Scott investigates unusually high suicide rates in Guyana, Greenland, and Siberian regions, exploring potential ethnic, cultural, and social factors contributing to these trends. Longer summary

This post explores unusually high suicide rates in different parts of the world, focusing on Guyana, Greenland, and remote Siberian regions. Scott examines potential causes for these high rates, including ethnic and cultural factors, alcohol consumption, social disruption, and abuse. For Guyana, he notes the high rate among Indo-Guyanese, speculating on possible cultural or historical reasons. In Greenland, he discusses the dramatic increase in suicide rates since the 1970s, linking it to forced modernization and a spike in alcohol consumption. For Siberian groups, he explores various theories including genetics and cultural traditions, but ultimately suggests that the combination of alcohol-naive hunter-gatherers, high alcohol consumption, and disruption of traditional ways of life may be the primary factors across these regions. Shorter summary

Scott Alexander shares a diverse collection of interesting links and news items, covering topics from historical anecdotes to recent scientific studies and cultural trends. Longer summary

This post is a collection of interesting links and news items from various fields. It covers topics such as historical anecdotes, scientific studies, political developments, technological innovations, and cultural trends. The author, Scott Alexander, provides brief summaries and sometimes adds his own commentary or humorous observations. The post touches on subjects like cryptocurrency, open access scientific publishing, genetic research, social media effects on polarization, and artificial intelligence developments. It also includes updates on ongoing stories and mysteries, such as the illness affecting US diplomats and the discovery of ancient skeletons in Tibet. Shorter summary

This Adversarial Collaboration Contest entry examines the evidence and debates surrounding transgender children transitioning, covering desistence rates, social transitioning, puberty blockers, and mental health outcomes. Longer summary

This post is an entry to the Adversarial Collaboration Contest, examining the complex issue of whether transgender children should transition. It covers topics such as gender dysphoria, desistence rates, social transitioning, puberty blockers, and mental health outcomes. The authors present evidence from various studies and narratives, discussing the potential benefits and risks of different approaches to supporting gender dysphoric youth. They conclude by summarizing the current state of knowledge on desistence, social transitioning, and puberty blockers, highlighting areas where more research is needed. Shorter summary

Scott Alexander shares a diverse collection of interesting links on topics ranging from science and politics to economics and culture, with brief commentary on many items. Longer summary

This post is a collection of links to various interesting articles, studies, and news items. It covers a wide range of topics including scientific discoveries, political events, economic trends, technological advancements, and cultural phenomena. Scott Alexander provides brief commentary on many of the links, often adding context or his own thoughts. The tone is informative and occasionally humorous, with a focus on sharing intriguing information across diverse fields. Shorter summary

Scott Alexander shares a diverse collection of interesting links on topics ranging from geography and drug policy to technology and economics, with brief summaries and comments. Longer summary

This post is a collection of links to various interesting articles, studies, and news stories. It covers a wide range of topics including geography, drug policy, technology, history, economics, science, and politics. Scott Alexander provides brief summaries or comments on each link, often with a touch of humor or irony. The post doesn't have a central theme but rather serves as a curated list of diverse and intriguing information from various fields. Shorter summary

The post criticizes the gendered framing of sexual harassment, presenting statistics on male victims and female perpetrators, and argues for a more balanced approach to the issue. Longer summary

This post critiques the gendered nature of sexual harassment discourse, arguing that it ignores male victims and female perpetrators. The author presents statistics showing that about 30% of sexual harassment victims are men and 20% of perpetrators are women. He argues that the media and society have framed sexual harassment as a exclusively male-on-female issue, silencing male victims and ignoring female perpetrators. The post suggests that this framing is deliberate and counterproductive, preventing a full understanding of the issue and making it harder for all victims to get justice. The author advocates for treating sexual harassment more like terrorism - as a universal problem that can be perpetrated by anyone, regardless of gender. Shorter summary

A collection of links covering topics from drug regulation and genetic testing to tax reform and AI developments, with Scott's commentary on each item. Longer summary

This is a wide-ranging links post covering various news items and studies. Topics include FDA regulations and drug pricing, genetic testing advances, Russian Facebook ads from the 2016 election, studies on education and intelligence, tax reform effects on graduate students, and various scientific developments. The post moves quickly between topics, providing brief commentary and often linking to additional sources. Several items focus on medical and healthcare issues, from insulin prices to studies on pain medication effectiveness. The post maintains Scott's characteristic mix of intellectual curiosity and light humor throughout. Shorter summary

A collection of interesting links covering topics from ancient Roman demographics to modern AI developments, criminal justice issues, and cultural oddities. Longer summary

This is a links post collecting various interesting news and articles. Topics include ancient Roman life expectancy data, Chinese censorship expanding to group chats, cruise ship pollution, AI developments like AlphaGo Zero, criminal justice issues around drug rehab work camps and police body cameras, and various other scientific, technological and cultural items. The post maintains a light tone while covering both serious topics like Puerto Rico's ongoing crisis and quirky ones like Viking reenactors and Halloween costumes. Shorter summary

Scott reviews a theory about serotonin receptors that explains how they help cope with stress, and discusses its implications and limitations. Longer summary

This post reviews a theory about serotonin receptors proposed by Robin Carhart-Harris and David Nutt. The theory focuses on two key receptors: 5-HT1A and 5-HT2A. It suggests that 5-HT1A promotes 'passive coping' (stoicism, bearing stress), while 5-HT2A promotes 'active coping' (increasing brain plasticity to find new solutions). The author finds the theory plausible and explains how it accounts for various effects of antidepressants and psychedelics. However, he also points out some remaining questions and potential biases in the theory. The post combines a detailed explanation of the theory with critical analysis and broader reflections on brain function and drug effects. Shorter summary

Scott Alexander shares interesting links on diverse topics including Russian life comparisons, AI developments, scientific discoveries, cultural evolution, and various research findings, with brief commentary on each. Longer summary

This is a links post collecting various interesting articles and news items. The topics range from historical curiosities like forest rings and 18th century sci-fi to modern developments in AI and genetics. There are several items about scientific research, including studies on autism, addiction, and serotonin. The post also covers cultural and social issues like the 'Mizzou Effect' at colleges and racial segregation patterns. Each item is briefly summarized with Scott's characteristic mix of intellectual curiosity and light commentary. Shorter summary

A collection of interesting links from early 2017 covering drugs, education, politics, science and history, with Scott's commentary on each. Longer summary

This is a links post where Scott Alexander shares various interesting articles and studies he's come across. The post covers a wide range of topics including new drug developments, education statistics, political events around Trump's presidency, scientific discoveries, and historical curiosities. The format follows a typical links post structure with brief commentary on each link, often adding context or witty observations. Many items focus on current events from early 2017, including Trump administration policies and European political trends. Shorter summary

A diverse collection of links covering current events, scientific studies, and cultural developments, with brief commentary on each story's significance or implications. Longer summary

This is a collection of links covering various topics from current events, science, and culture. It includes news about the seasteading institute's deal with French Polynesia, a meta-analysis on red meat and cardiovascular disease, a discussion of authoritarianism by Tom Pepinsky, and various studies on topics like growth mindset and the Flynn Effect. The links also cover political developments like Obama's attempts to close Guantanamo, Trump's health picks, and new research on school choice experiments. The post maintains a neutral tone while providing brief commentary and context for each link. Shorter summary

A links post featuring various news and articles about politics, science, and culture, with Scott's commentary on research papers and current events. Longer summary

This is a links post compiling various interesting news and articles from around the web. Topics range from climate change and politics to scientific studies and charitable giving. Scott comments on several research papers, including ones about non-citizen voting and healthcare in Cuba. The post also includes interesting side notes about geography, prison marriages, and literary references. Many of the links are accompanied by Scott's brief commentary or witty observations. Shorter summary

A links post featuring stories about AI research, scientific studies, historical oddities, and current events, ranging from antibacterials in soap to disco riots at baseball games. Longer summary

This is a links post collecting various interesting stories and studies. It covers topics ranging from AI research (including MIRI's new paper on Logical Induction and UC Berkeley's new AI safety center), scientific findings (about school entry age and journal quality), historical oddities (like Disco Demolition Night and pay toilets), and current events (like the kratom ban and Seattle's microhousing). The post demonstrates Scott's typical mix of academic research, policy analysis, and interesting historical anecdotes, all tied together with his characteristic dry humor. Shorter summary

Scott Alexander distinguishes between 'universal culture' and 'Western culture', exploring how the former outcompetes all traditional cultures and the ethical implications of this process. Longer summary

Scott Alexander discusses the concept of 'universal culture' as distinct from 'Western culture', arguing that what is often called 'Westernization' is actually the spread of a culture optimized for industrial societies. He explains how this universal culture outcompetes traditional cultures, including Western culture itself, and explores the ethical implications of this process. The post concludes by considering whether we should support or resist the spread of universal culture, acknowledging the complexity of the issue without reaching a definitive stance. Shorter summary

Scott Alexander criticizes media tendencies to label politicians as racist or sexist based on ambiguous statements, arguing we should focus more on their stated positions and actions. Longer summary

Scott Alexander criticizes the media's tendency to label politicians as racist or sexist based on ambiguous statements or 'dog whistles'. He argues this often ignores the politicians' actual stated beliefs and policies in favor of overanalyzing gaffes or interpreting statements as secret codes. The post examines three cases: Ted Cruz being called anti-Semitic for saying 'New York values', Ken Livingstone being labeled anti-Semitic for comments about Hitler and Zionism, and Donald Trump being called openly sexist despite his pro-women hiring record. Scott suggests we should be more skeptical of media claims to have special insight into politicians' true beliefs and instead focus on their stated positions and past actions. Shorter summary

A collection of interesting links and studies on various topics, from bad statistics and media coverage to technological progress and scientific discoveries, with commentary from Scott Alexander. Longer summary

This is one of Scott's regular link posts, presenting a diverse collection of interesting articles, studies, and developments. The topics range from media coverage and politics, through scientific studies and technological progress, to social developments and cultural phenomena. Scott provides commentary on many of the links, often adding context, questioning methodology, or highlighting interesting implications. The post maintains a mix of serious academic content and lighter cultural observations. Shorter summary

Scott shares diverse links ranging from optical illusions and Bitcoin drama to educational research and medical controversies, with commentary on methodology and social implications. Longer summary

A collection of interesting links covering various topics. The post starts with scientific curiosities like the McCullough Effect optical illusion and updates on potential alien megastructures, then moves through educational research, Bitcoin controversies, and employment discrimination. It includes discussions of medical issues in the UK, interesting methodologies in gender research, and immigration policies. The post ends with various studies on economics, psychology, and social issues, including an intriguing study about Vietnam veterans' children's income. Shorter summary

Scott shares a diverse collection of interesting links spanning science, history, and current events, with commentary on research methodologies and unexpected findings. Longer summary

A collection of interesting links and studies across various topics. The post covers scientific studies (like ego depletion and male variability), historical curiosities (like Russian Somalia and Project Oilsand), current events (Jeremy Corbyn's election), and various social and political developments. Scott presents each item with brief commentary, often highlighting interesting methodologies or unexpected findings. The post maintains a mix of serious academic content and more lighthearted observations, frequently noting clever research designs or counterintuitive findings. Shorter summary

A collection of interesting links covering various topics including medical discoveries, scientific studies, social issues, and economic findings, with brief commentary on each. Longer summary

This is a links post collecting various interesting articles and studies. The topics range from medical discoveries to economics, from social issues to scientific studies. It includes discussions of the Brindley lecture in urology, property rights on the moon, fecal transplant effects on weight, mental health policies at Yale, studies on criminality and parenting, and various other scientific and social findings. The post presents each link with a brief commentary or explanation, often with Scott's characteristic mix of curiosity and skepticism. Shorter summary

A collection of interesting links covering topics from werewolf-related customs in Argentina to scientific studies, economic trends, and cultural phenomena. Longer summary

This is a links post featuring a diverse collection of interesting stories and studies. It includes quirky historical facts like Argentina's president being godfather to potential werewolves and Byzantine throne customs, scientific studies about gender bias in maritime disasters and climate change controversies, and current events like Russian economic problems and protests against police brutality. The post also covers technological developments in nuclear rockets and desalination, architectural projects, and various social and economic issues. Scott presents these with his characteristic analytical commentary and occasional humor. Shorter summary

A links roundup covering topics from ISIS dating sites to space exploration, scientific studies, and cultural observations, featuring Scott's commentary and analysis on each item. Longer summary

This is a links post presenting various news and studies. It covers diverse topics including a dating site run by ISIS, space exploration news about Orion and SpaceX, studies about omega-3 fats and psychosis, Chinese censorship of puns, controversies around doxxing in Ferguson, research on glial cells and intelligence, poker tournament winners linked to effective altruism, and various other scientific studies and cultural observations. Shorter summary